mouse monoclonal IgG1; PGRP-S Antibody (G-1) is an IgG1 κ mouse monoclonal PGRP-S antibody (also designated PGRP-S antibody) that detects the PGRP-S protein of mouse origin by WB, IP, IF and ELISA. PGRP-S Antibody (G-1) is available as both the non-conjugated anti-PGRP-S antibody form, as well as multiple conjugated forms of anti-PGRP-S antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Peptidoglycan recognition proteins (PGRPs) are molecules that recognize peptidoglycan, a large component in bacterial cell walls. In insects, PGRPs activate antimicrobial pathways, and in mammals PGRPs function as antibacterial neutrophil proteins. PGRP-L halts bacterial growth by acting as an alanine amidase, an enzyme that hydrolyzes the amide bond of bacterial peptidoglycan. PGRP-Iα and PGRP-Iβ are also members of the PGRP family that help recognize bacteria by binding to peptidoglycan and Gram-positive bacteria, but they do not have amidase activity. PGRP-S participates in intracellular killing of Gram-positive bacteria by stimulating two antimicrobial defense systems, the prophenoloxidase cascade and the antimicrobial peptides through Toll receptors.