Manufacturing of proteins, mRNA or small molecules requires comprehensive strain engineering approaches to increase yield, productivity, and robustness of the strain. While some of these goals can be accomplished with standard genetic engineering methods, others require a whole-genome, exploratory approach that can take many months. With the Onyx® Digital Genome Engineering platform, you can go after each of these objectives simultaneously by generating diverse strain libraries in a simple, automated workflow. Insertions, deletions, and substitutions across multiple targets, such as promoters, coding regions or global regulators, can be rapidly introduced to improve both specific functions and the overall manufacturability of the strain. In this webinar we will demonstrate how this approach helped improve production of heterologous proteins in E. coli and S. cerevisiae.   

 

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