Medical Director: Special Chemistry and Endocrinology - Assistant Professor, University of Utah School of Medicine
BIOGRAPHY
DEC 04, 2020 8:00 AM PST
Analytical Limitations of HbA1c: Factors to consider when choosing an HbA1c Methodology
Speakers
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Randie R. Little
Director, Diabetes Diagnostic Laboratory (DDL) - Network Coordinator, NGSPBIOGRAPHY -
David B. Sacks
Senior Investigator - Chief, Clinical Chemistry Service - NIHBIOGRAPHY
Event Date & Time
DATE: December 4th, 2020
TIME: 8:00am PT
Abstract
With many methods available for HbA1c testing, how do you choose a method that’s best for your laboratory? The incidence and prevalence of diabetes mellitus is on the rise, and so is the use of HbA1c in the clinical laboratory. HbA1c is routinely used as the gold standard test to monitor, diagnose, and manage diabetic patients. However, there are several limitations to HbA1c as an assay in diabetes screening, including methodology, analytical interference, and biological interference. Different methodologies exist today to measure HbA1c such as immunoassay, enzymatic, HPLC and capillary electrophoresis. While many commercial methodologies are standardized, what are the limitations to each of these methods? What do you need to consider when choosing an HbA1c method for your laboratory?
Learning Objectives:
- Review methods available for measuring HbA1c in the clinical laboratory.
- Understand standardization of measuring HbA1c.
- Examine clinical utility of different HbA1c assays.
- Evaluate factors to consider when selecting an HbA1c method in your laboratory.
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