Professor of Anesthesiology and Critical Care & Professor of Surgery (Cardiothoracic) - Duke University School of Medicine
BIOGRAPHY
Friday, April 28th, 12:00AM EST
Heparin Resistance in Critically Ill Patients: Best Practices Using Laboratory Coagulation Assays
SPECIAL EDUCATIONAL EVENT IN HONOR OF ASCLS LAB WEEK 2023
Presented at:
Stago EdVantage Virtual University
Speaker
Abstract
Heparin Resistance in Critically Ill Patients: Best Practices Using Laboratory Coagulation Assays
Hospitalized patients with various underlying illnesses are routinely given parenterally administered unfractionated heparin (UFH) in order to prevent and/or treat thromboembolic events. In some cases, despite being given heparin, laboratory tests intended to monitor the UFH may report the patient has not reached the targeted therapeutic range. The observed response is considered “heparin resistance” in clinical practice and can create confusion for patient management. Our webinar will discuss clinical scenarios around heparin resistance, recommended approaches for laboratory testing when observed, including the role of chromogenic anti-Xa testing, and patient case studies.
Learning Objectives
- Describe common scenarios resulting in heparin resistance observed in clinical settings
- Demonstrate clinical management approaches for patients exhibiting heparin resistance, including the role of anti-Xa testing
- Illustrate the impact of discordance between anti-Xa vs. aPTT and activated clotting time (ACT) in patients exhibiting heparin resistance
- Provide case studies illustrating clinical management and impact on potential heparin resistant patient testing
