Over the past 25 years many advances in techniques have been incorporated into infectious disease research. From genetically modified animals to advances in basic techniques that improve results much has changed. However, many other core principles are just as critical now as they were then and tend to be forgotten in the rush to incorporate new technologies. This presentation will discuss what has changed in the last quarter century for in vivo research including new technologies and techniques as well as point out some critical concepts that deserve to remain in consideration.  

Learning Objectives: 

1. Demonstrate the need for a high level of technical skill and understanding to generate high quality data while maintaining the appropriate welfare of our animals
2. Identify key components for high level study execution