Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.
FMC63 is a CD19-specific IgG1 mouse monoclonal antibody, which is a target for immunotherapy of B-lineage leukemia and lymphoma. FMC63 scFv is the most commonly used extracellular domain component of CD19-specific CARs. So far, most of the reported CART-CD19 clinical trials contain anti-CD19 scFv derived from FMC63, such as the two FDA-approved CARs Kymriah and Yescarta. This product was verified to specifically recognize the antigen recognition domain of FMC63-derived CAR.
Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.