mouse monoclonal IgG1; Syntaxin 1 Antibody (HPC-1) is an IgG1 κ mouse monoclonal Syntaxin 1 antibody (also designated Syntaxin antibody, Syntaxin-1A antibody or STX1A antibody) that detects the Syntaxin 1 protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. Syntaxin 1 Antibody (HPC-1) is available as both the non-conjugated anti-Syntaxin 1 antibody form, as well as multiple conjugated forms of anti-Syntaxin 1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Correct vesicular transport is essential to the survival of eukaryotic cells. This process is determined by specific pairing of vesicle-associated SNAREs (v-SNAREs) with those on the target membrane (t-SNAREs). This complex then recruits soluble NSF attachment proteins (SNAPs) and N-ethylmaleimide-sensitive factor (NSF) to form the highly stable SNAP receptor (SNARE) complex. The formation of a SNARE complex pulls the vesicle and target membrane together and may provide the energy to drive fusion of the lipid bilayers. SNAPs, including a- and g-SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and Syntaxin 1. Syntaxins, including Syntaxin 1, comprise a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane. The Syntaxin family displays broad tissue distribution and contains C-terminal hydrophobic domains that direct them to their respective intracellular compartments.