mouse monoclonal IgG2b; TCP-10 Antibody (E-6) is an IgG2b κ mouse monoclonal TCP-10 antibody (also designated TCP-10 antibody) that detects the TCP-10 protein of human origin by WB, IP, IF and ELISA. TCP-10 Antibody (E-6) is available as both the non-conjugated anti-TCP-10 antibody form, as well as multiple conjugated forms of anti-TCP-10 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. TCP-10 (t-complex 10 homolog), also known as TCP10A, is a 353 amino acid protein belonging to the TCP10 family. TCP-10 exists as two alternatively spliced isoforms and is encoded by a gene located human chromosome 6q27. Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6.