Santa Cruz Biotechnology

CAD (H-1) AC | Santa Cruz Biotechnology

(0) Write Review

mouse monoclonal IgG2b; The Ced/ICE or caspase family of cysteine proteases plays a pivotol role in mediating apoptosis through the proteolysis of specific targets. Among the targets are poly(ADP-ribose) polymerase (PARP), Gelsolin, ICAD (inhibitor of CAD, also designated DFF-45) and the nuclear lamins. CAD (caspase-activated deoxyribonuclease), also designated CPAN (caspase-activated nuclease) and DFF40, is a DNase that is responsible for DNA degradation during apoptosis. Caspase-3 acts to dissociate CAD from ICAD, allowing CAD to enter the nucleus and degrade DNA.

Learn More

Reviews

(0) | Be the first to review this product
No reviews yet
Scientific Products
  • See More
    • Upcoming Virtual Events
    Upcoming Webinars