mouse monoclonal IgG1; Cdc2 p34 Antibody (B-6) is an IgG1 κ mouse monoclonal Cdc2 p34 antibody that detects Cdc2 p34 of mouse, rat and human origin by WB, IP, IF and ELISA. Cdc2 p34 Antibody (B-6) is available as the non-conjugated anti-Cdc2 p34 antibody form, as well as multiple conjugated forms of anti-Cdc2 p34 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. In vertebrates, as in yeast, multiple cyclins have been identified, including a total of eight such regulatory proteins in mammals. In contrast to the situation in yeast, the Cdc2 p34 kinase is not the only catalytic subunit identified in vertebrates that can interact with cyclins. While Cdc2 p34 is essential for the G2 to M transition in vertebrate cells, a second Cdc2-related kinase has also been implicated in cell cycle control. This protein, designated cyclin-dependent kinase 2 (Cdk2) p33, also binds to cyclins and its kinase activity is temporally regulated during the cell cycle. Several additional Cdc2 p34-related cyclin dependent kinases have been identified. These include Cdk3-Cdk8, PCTAIRE-1-3 and KKIALRE.