Santa Cruz Biotechnology

FGF-9 (D-8) | Santa Cruz Biotechnology

mouse monoclonal IgG3; FGF-9 Antibody (D-8) is an IgG3 mouse monoclonal FGF-9 antibody that detects precursor and mature FGF-9 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. FGF-9 Antibody (D-8) is available as the non-conjugated anti-FGF-9 antibody form. Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithe-lial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10-FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family including four tyrosine kinases, designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.

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