Research models are used in medical research to mimic aspects of a disease or illness that occurs in humans. Research models can include animals (in vivo models), cell lines (in vitro models), or computer-driven demonstrations (in silico models). Research models allow doctors and scientists to uncover important information that can be applied to clinical practice.
Impulsivity can be defined as the tendency to act prematurely without foresight. Behavioural and neurobiological analysis of this construct, based on evidence from both animal and human studi...
The hippocampal formation is one of the most extensively studied regions of the brain, with well described anatomy and basic physiology; moreover, aspects of human memory mediated by hippocam...
Schizophrenia is a severe psychiatric disorder affecting 1% of the world’s population, leading to high human, social and economic burdens. Understanding how the interaction of gene and...
The dopamine-containing neurons of the midbrain have been implicated in a broad array of psychiatric disorders, ranging from schizophrenia to drug abuse and depression. However, studies seem...
As evidenced by the changes in the new Guide for the Care and Use of Laboratory animals and the latest AVMA Panel on Euthanasia, it is clear that there is growing concern about the care and w...
The management of animal research programs has evolved into a complex and multifaceted endeavor. Scientific discovery moves at a fast pace and our knowledge of animal science is continually...
The pre-operative assessment and post-operative is critical for successful surgical procedures which will in turn lead to high quality outcomes in research studies. The care of the animals go...
In the context of an experimental project requiring surgical preparation of animals, training is not only required for technicians lacking a strong surgical background but also for more exper...
Effective workplace training in a research facility is an important key in ensuring smooth operations and high standards of animal care. Today's diverse workforce offers many benefits such a...
Recent advances in anesthesia, monitoring, pain assessment and analgesia provide many opportunities for improving the quality of our in vivo scientific data, and promoting high standards of a...
An anesthesia system designed to accommodate the physiological characteristics of small animals, including rats and mice, has the potential to provide great practical value to the life scienc...
Fish are vertebrates but they are physiologically and psychologically different from mammals. This presentation will try to explain their differences from mammals and the different aspects t...
Laboratory animal surgical models are instrumental in biomedical research; therefore establishing healthy defined animal models is crucial to this research. Surgical procedures produce metab...
Many researchers are not aware of the critical importance of genetic background of mice, including the concept of inbred substrains, and how the genetic background of substrains can impact th...
The field of surgical research has been growing rapidly with the development of new surgical and disease models. An extremely important and often overlooked aspect of creating these models is...
In Chile, the regulatory context regarding animal use in research is very poor. A legal framework for Animal Care and Use Committees is practically nonexistent. Also, the chilean culture play...
It is the often-ignored simple tips in rodent surgery that make the difference and help minimize postoperative complications and mortality. The presenter will use his years of experience to...
Some commonly accepted principles of biosafety include the strict adherence to standard laboratory practices and techniques, the use of safety equipment such as primary barriers and personal...
During my presentation, we will discuss:- Normal patterns of behavior (repertoire): social, food intake, territorial, agonistic, anti-predation, sleep and rest, play behavior, grooming, sex...
The transportation of laboratory animals is a critical step in obtaining the proper strain of animal that best fits the researchers needs. Animal Extremist groups have made this transportati...
Soiled-bedding sentinels are not always efficient in detecting pathogens in rodent colonies. In this context, PCR-based testing can be more sensitive and is being advocated as adjunct to trad...
Adherence to strict aseptic technique is vital to all types of animal models requiring surgical intervention from both scientific and welfare perspectives. Training of both new and experience...
Drug developers are rapidly adopting three-dimensional (3D) cell cultures for drug screening since they provide a more physiologically relevant environment than two-dimensional cell cultures ...
Mass spectrometry (MS)-based profiling of clinical specimens has been increasingly used in cancer research to characterize changes in protein expression between tumor and healthy tissue or be...
Impulsivity can be defined as the tendency to act prematurely without foresight. Behavioural and neurobiological analysis of this construct, based on evidence from both animal and human studi...
The hippocampal formation is one of the most extensively studied regions of the brain, with well described anatomy and basic physiology; moreover, aspects of human memory mediated by hippocam...
Schizophrenia is a severe psychiatric disorder affecting 1% of the world’s population, leading to high human, social and economic burdens. Understanding how the interaction of gene and...
The dopamine-containing neurons of the midbrain have been implicated in a broad array of psychiatric disorders, ranging from schizophrenia to drug abuse and depression. However, studies seem...
As evidenced by the changes in the new Guide for the Care and Use of Laboratory animals and the latest AVMA Panel on Euthanasia, it is clear that there is growing concern about the care and w...
The management of animal research programs has evolved into a complex and multifaceted endeavor. Scientific discovery moves at a fast pace and our knowledge of animal science is continually...
The pre-operative assessment and post-operative is critical for successful surgical procedures which will in turn lead to high quality outcomes in research studies. The care of the animals go...
In the context of an experimental project requiring surgical preparation of animals, training is not only required for technicians lacking a strong surgical background but also for more exper...
Effective workplace training in a research facility is an important key in ensuring smooth operations and high standards of animal care. Today's diverse workforce offers many benefits such a...
Recent advances in anesthesia, monitoring, pain assessment and analgesia provide many opportunities for improving the quality of our in vivo scientific data, and promoting high standards of a...
An anesthesia system designed to accommodate the physiological characteristics of small animals, including rats and mice, has the potential to provide great practical value to the life scienc...
Fish are vertebrates but they are physiologically and psychologically different from mammals. This presentation will try to explain their differences from mammals and the different aspects t...
Laboratory animal surgical models are instrumental in biomedical research; therefore establishing healthy defined animal models is crucial to this research. Surgical procedures produce metab...
Many researchers are not aware of the critical importance of genetic background of mice, including the concept of inbred substrains, and how the genetic background of substrains can impact th...
The field of surgical research has been growing rapidly with the development of new surgical and disease models. An extremely important and often overlooked aspect of creating these models is...
In Chile, the regulatory context regarding animal use in research is very poor. A legal framework for Animal Care and Use Committees is practically nonexistent. Also, the chilean culture play...
It is the often-ignored simple tips in rodent surgery that make the difference and help minimize postoperative complications and mortality. The presenter will use his years of experience to...
Some commonly accepted principles of biosafety include the strict adherence to standard laboratory practices and techniques, the use of safety equipment such as primary barriers and personal...
During my presentation, we will discuss:- Normal patterns of behavior (repertoire): social, food intake, territorial, agonistic, anti-predation, sleep and rest, play behavior, grooming, sex...
The transportation of laboratory animals is a critical step in obtaining the proper strain of animal that best fits the researchers needs. Animal Extremist groups have made this transportati...
Soiled-bedding sentinels are not always efficient in detecting pathogens in rodent colonies. In this context, PCR-based testing can be more sensitive and is being advocated as adjunct to trad...
Adherence to strict aseptic technique is vital to all types of animal models requiring surgical intervention from both scientific and welfare perspectives. Training of both new and experience...
Drug developers are rapidly adopting three-dimensional (3D) cell cultures for drug screening since they provide a more physiologically relevant environment than two-dimensional cell cultures ...
Mass spectrometry (MS)-based profiling of clinical specimens has been increasingly used in cancer research to characterize changes in protein expression between tumor and healthy tissue or be...
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