The universe contains all of space, time, matter, and energy. The observable universe measures approximately 93 billion light-years in diameter today, although the size of the entire universe remains unknown.
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Biocatalysis, protein engineering, and flow chemistry are key enabling technologies that can yield drastically shorter and greener chemical processes. We sought to leverage these technologie...
Learning Objectives: 1. CRISPR-Cas systems are naturally repurposes for non-canonical functions other than cleaving RNA and DNA 2. CRISPR RNA-guided transposases integrate donor DNA without...
Genome Engineering allows the easy manipulation of genomes down to the nucleotide level. CRISPR is a revolutionizing tool for generating custom edited cell and pre-clinical animal models for...
We have harnessed homologous recombination to modify the genome of human stem cells with high frequencies (>40%). By designing the recombination donor in different ways, we can achieve a...
Gene editing technologies such as CRISPR/Cas9 have greater flexibility and high efficiency. CRISPR technology enables targeted insertion of transgenes at the desired locus and has the abilit...