Antibody Validation: Antibody binding affinity is another parameter that can be used for antibody validation. It refers to the strength with which an antibody molecule binds an epitope.
The detection of circulating molecular biomarkers is useful for monitoring pathogenic processes and response to therapeutic intervention1,2. In cancer, genomic and proteomic biomarkers are us...
In order to expand the treatment options of cancers driven by oncogenic RAS, new cell surface targets need to be identified and characterized. Here, we describe mass spectrometry based phenot...
DATE: September 19, 2017TIME: 10:30am PDT/ 1:30pm EDT/ 7:30pm CESTPart 1 – Cigall Kadoch, Ph.D. (30 min.)Exome- and genome-wide sequencing studies in human cancer have...
DATE: September 12, 2017TIME: 8:00am PT, 11:00am ETEvery year, millions of dollars are wasted on poorly characterized and performing antibodies. Key researchers in the antibody co...
DATE: June 6, 2017TIME: 8:00am PT, 11:00am ETEarly detection of protein biomarkers is critical to the study of human disease (cancer, neurobiology, inflammation/autoimmunity, etc)....
Addressing the antibody reproducibility crisis: A panel discussion with key scientific leaders Reproducibility and antibody validation standards are two significant challenges f...
Often we are concerned at the thought of a lab run by robots, not humans-- but what if instead of having the world's brightest minds concerned with pipetting, blotting and scanning, there...
DATE: May 22, 2017TIME: 8:00AM PDT, 11:00AM ETCrohn's disease (CD) results from a complex interplay between host genetic factors and endogenous microbial communities. In the current...
DATE: May 18, 2017TIME: 8:00AM PDT, 11:00AM ETIt is well established that ligand binding can protect proteins from thermal denaturation in a cellular milieu; however, the broad applicat...
The objective of academic, biotech or pharmaceutical scientists committed to protein purification is to obtain the purest protein needed for their application, regardless of scale. Towards th...
Healthcare is becoming more proactive and data-rich than anything before possible – and will increasingly focus on maintaining and enhancing wellness more than just reacting to disease....
In this era of precision molecular medicine, knowledge changes rapidly and is highly dispersed. Physicians and patients are faced with conflicting expert opinions and a shortage of acti...
Liquid Biopsies are gaining acceptance in the Oncology community as a surrogate or complement to the gold standard of tissue biopsy. A liquid biopsy provides biomarker information that...
Much has been made in the popular press about importance of our "genes" in everything from our weight, intelligence, and our risk of disease. While there is a scientific basis...
Launched in early 2015, the Precision Medicine Initiative (PMI) takes advantage of the progress made in genomic testing – progress largely driven by rapid advances in DNA sequencing tec...
DATE: January 27, 2017TIME: 4:00am PT, 7:00am ET, 1:00pm CETThe study of the tumor ecosystem and its cell-to-cell communications is essential to enable an understanding of tumor biology...
Review tips and techniques on how to get the best out of your experiments and overcome the most common technical challenges with our resident IHC/ICC specialist.Topics reviewed include:...
Antibodies are used in a broad range of research and diagnostic applications for the enrichment, detection, and quantitation of proteins and their modifications. Hundreds of thousands o...
We describe a novel method to measure 1,25(OH)2D. Briefly, this method was built on four pillars: (1) the nuclear vitamin D receptor (VDR)`s ligand binding domain (LBD) as a capture mol...
The recent Zika virus outbreak highlights the need for low-cost diagnostics that can be rapidly developed for distribution and use in pandemic regions. In early 2016 we developed a pipe...
DATE: October 27, 2016
TIME: 9:00am PT, 12:00pm ET
The importance of antibodies as tools in scientific research studies cannot be understated, yet these reagents have increasi...
DATE: September 22, 2016
TIME: 4:00am PT, 7:00am ET, 11:00am GMT
Here, we present a novel approach that combines the principles of the western blot (protein separation by SDS-PAGE; ...
Antibodies are tremendously useful and versatile tools and they have found use in many areas of life science research. However, antibodies can be difficult to make and are used in inherently...
DATE: June 14, 2016TIME: 8am Pacific time, 11am Eastern timeImproving systems for rapid small-scale protein purification and analysis in order to obtain sample numbers for statist...
The detection of circulating molecular biomarkers is useful for monitoring pathogenic processes and response to therapeutic intervention1,2. In cancer, genomic and proteomic biomarkers are us...
In order to expand the treatment options of cancers driven by oncogenic RAS, new cell surface targets need to be identified and characterized. Here, we describe mass spectrometry based phenot...
DATE: September 19, 2017TIME: 10:30am PDT/ 1:30pm EDT/ 7:30pm CESTPart 1 – Cigall Kadoch, Ph.D. (30 min.)Exome- and genome-wide sequencing studies in human cancer have...
DATE: September 12, 2017TIME: 8:00am PT, 11:00am ETEvery year, millions of dollars are wasted on poorly characterized and performing antibodies. Key researchers in the antibody co...
DATE: June 6, 2017TIME: 8:00am PT, 11:00am ETEarly detection of protein biomarkers is critical to the study of human disease (cancer, neurobiology, inflammation/autoimmunity, etc)....
Addressing the antibody reproducibility crisis: A panel discussion with key scientific leaders Reproducibility and antibody validation standards are two significant challenges f...
Often we are concerned at the thought of a lab run by robots, not humans-- but what if instead of having the world's brightest minds concerned with pipetting, blotting and scanning, there...
DATE: May 22, 2017TIME: 8:00AM PDT, 11:00AM ETCrohn's disease (CD) results from a complex interplay between host genetic factors and endogenous microbial communities. In the current...
DATE: May 18, 2017TIME: 8:00AM PDT, 11:00AM ETIt is well established that ligand binding can protect proteins from thermal denaturation in a cellular milieu; however, the broad applicat...
The objective of academic, biotech or pharmaceutical scientists committed to protein purification is to obtain the purest protein needed for their application, regardless of scale. Towards th...
Healthcare is becoming more proactive and data-rich than anything before possible – and will increasingly focus on maintaining and enhancing wellness more than just reacting to disease....
In this era of precision molecular medicine, knowledge changes rapidly and is highly dispersed. Physicians and patients are faced with conflicting expert opinions and a shortage of acti...
Liquid Biopsies are gaining acceptance in the Oncology community as a surrogate or complement to the gold standard of tissue biopsy. A liquid biopsy provides biomarker information that...
Much has been made in the popular press about importance of our "genes" in everything from our weight, intelligence, and our risk of disease. While there is a scientific basis...
Launched in early 2015, the Precision Medicine Initiative (PMI) takes advantage of the progress made in genomic testing – progress largely driven by rapid advances in DNA sequencing tec...
DATE: January 27, 2017TIME: 4:00am PT, 7:00am ET, 1:00pm CETThe study of the tumor ecosystem and its cell-to-cell communications is essential to enable an understanding of tumor biology...
Review tips and techniques on how to get the best out of your experiments and overcome the most common technical challenges with our resident IHC/ICC specialist.Topics reviewed include:...
Antibodies are used in a broad range of research and diagnostic applications for the enrichment, detection, and quantitation of proteins and their modifications. Hundreds of thousands o...
We describe a novel method to measure 1,25(OH)2D. Briefly, this method was built on four pillars: (1) the nuclear vitamin D receptor (VDR)`s ligand binding domain (LBD) as a capture mol...
The recent Zika virus outbreak highlights the need for low-cost diagnostics that can be rapidly developed for distribution and use in pandemic regions. In early 2016 we developed a pipe...
DATE: October 27, 2016
TIME: 9:00am PT, 12:00pm ET
The importance of antibodies as tools in scientific research studies cannot be understated, yet these reagents have increasi...
DATE: September 22, 2016
TIME: 4:00am PT, 7:00am ET, 11:00am GMT
Here, we present a novel approach that combines the principles of the western blot (protein separation by SDS-PAGE; ...
Antibodies are tremendously useful and versatile tools and they have found use in many areas of life science research. However, antibodies can be difficult to make and are used in inherently...
DATE: June 14, 2016TIME: 8am Pacific time, 11am Eastern timeImproving systems for rapid small-scale protein purification and analysis in order to obtain sample numbers for statist...
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