Biology: the study of living organisms, divided into many specialized fields that cover their morphology, physiology, anatomy, behavior, origin, and distribution. This includes plants, animals, and other qualities of organisms or class of organisms.
CALIXAR has developed an innovative detergent/surfactant based approach consisting on native isolation and stabilization of therapeutic membrane protein targets such as GPCRs, ion channels, t...
DATE: May 9th, 2017TIME: 7:00AM PDT, 10:00AM ET, 2:00PM GMT Early detection and elimination of new chemical entities with cardiac or hERG liability could substantially improve...
Neurons derived from human pluripotent stem cells (hPSCs) and primary rodent neurons both are excellent resources for disease modeling and drug screening. Human PSCs derived neural stem...
Developing therapies for human diseases continues to face obstacles, particularly in translating targets or compounds identified by in vitro screening campaigns to valid targets or efficaciou...
DATE: April 20th, 2017TIME: 10:00AM SGT, 11:00AM KST, 12:00PM AEST, 2:00PM NZSTWith increasing breadth and depth of genomics studies across a range of cancers, it is now apparent that t...
DATE: April 18, 2017TIME: 7:30am PT, 10:30am ETLabs large and small that conduct genomic studies are looking for ways to vastly improve NGS sample prep, especially from challenging FFPE...
Next-generation sequencing is expected to take molecular diagnostics to the next level with the capability to perform deep analysis of genetic information that leads to targeted therapies per...
Genomics and metagenomics have become ubiquitous research efforts. Here we will show details of the development of physical, computational, and even space-based standards for metagenomi...
DATE: April 11, 2017TIME: 8:00 AM PT, 11:00 AM ET Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond....
DATE: April 6, 2017TIME: 3:00PM GMT, 7:00AM PT, 10:00AM ETThe Edinburgh Genome Foundry (EGF) is a newly established facility of the University of Edinburgh and ass...
CRISPR-Cas9 has increased the accessibility of genome engineering due to its ease of use and ability to cause double strand breaks (DSBs) at almost any locus of interest. DSBs are repaired in...
There is rapidly growing interest in using the CRISPR-Cas9 system for functional screening, both as a primary screening tool and as an orthogonal tool for RNAi hit validation. High throughput...
DATE: March 24th, 2017TIME: 7:30AM PT, 10:30AM ET There is a growing demand in the biopharmaceutical industry for rapid N-glycosylation profiling of therapeutic antibodies....
Studying the genetics of rare congenital disorders disrupting cognitive function has led to the identification of multiple disease genes that helped us better understand the mechanisms underl...
Alterations in homeostatic functions such as energy balance and sleep patterns are frequently seen in the elderly and these changes may precede and predict subsequent cognitive decline. ...
Epigenetics refers to the study of nuclear architecture and gene regulation. Epigenetic mechanisms govern many physiological processes such as cell differentiation, x-inactivation, and genomi...
Specialized aggregations of extracellular matrix called perineuronal nets (PNNs) appear during juvenile stages of development and surround primarily fast-spiking, parvalbumin (PV)-containing...
A fundamental challenge in developing brain machine interfaces (BMIs) is building a decoder between patterns of brain activity and movement in patients with spinal cord injury, ALS, and amput...
Gilles de la Tourette syndrome (GTS) is a neurodevelopmental disorder exhibiting both motor and behavioral impairment. Like most neuropsychiatric disorders, its pathophysiology has yet to be...
Basal forebrain cholinergic inputs to the cortex are known to contribute to attentional performance. A major focus of my laboratory has been to study the receptors mediating the effects of ac...
CALIXAR has developed an innovative detergent/surfactant based approach consisting on native isolation and stabilization of therapeutic membrane protein targets such as GPCRs, ion channels, t...
DATE: May 9th, 2017TIME: 7:00AM PDT, 10:00AM ET, 2:00PM GMT Early detection and elimination of new chemical entities with cardiac or hERG liability could substantially improve...
Neurons derived from human pluripotent stem cells (hPSCs) and primary rodent neurons both are excellent resources for disease modeling and drug screening. Human PSCs derived neural stem...
Developing therapies for human diseases continues to face obstacles, particularly in translating targets or compounds identified by in vitro screening campaigns to valid targets or efficaciou...
DATE: April 20th, 2017TIME: 10:00AM SGT, 11:00AM KST, 12:00PM AEST, 2:00PM NZSTWith increasing breadth and depth of genomics studies across a range of cancers, it is now apparent that t...
DATE: April 18, 2017TIME: 7:30am PT, 10:30am ETLabs large and small that conduct genomic studies are looking for ways to vastly improve NGS sample prep, especially from challenging FFPE...
Next-generation sequencing is expected to take molecular diagnostics to the next level with the capability to perform deep analysis of genetic information that leads to targeted therapies per...
Genomics and metagenomics have become ubiquitous research efforts. Here we will show details of the development of physical, computational, and even space-based standards for metagenomi...
DATE: April 11, 2017TIME: 8:00 AM PT, 11:00 AM ET Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond....
DATE: April 6, 2017TIME: 3:00PM GMT, 7:00AM PT, 10:00AM ETThe Edinburgh Genome Foundry (EGF) is a newly established facility of the University of Edinburgh and ass...
CRISPR-Cas9 has increased the accessibility of genome engineering due to its ease of use and ability to cause double strand breaks (DSBs) at almost any locus of interest. DSBs are repaired in...
There is rapidly growing interest in using the CRISPR-Cas9 system for functional screening, both as a primary screening tool and as an orthogonal tool for RNAi hit validation. High throughput...
DATE: March 24th, 2017TIME: 7:30AM PT, 10:30AM ET There is a growing demand in the biopharmaceutical industry for rapid N-glycosylation profiling of therapeutic antibodies....
Studying the genetics of rare congenital disorders disrupting cognitive function has led to the identification of multiple disease genes that helped us better understand the mechanisms underl...
Alterations in homeostatic functions such as energy balance and sleep patterns are frequently seen in the elderly and these changes may precede and predict subsequent cognitive decline. ...
Epigenetics refers to the study of nuclear architecture and gene regulation. Epigenetic mechanisms govern many physiological processes such as cell differentiation, x-inactivation, and genomi...
Specialized aggregations of extracellular matrix called perineuronal nets (PNNs) appear during juvenile stages of development and surround primarily fast-spiking, parvalbumin (PV)-containing...
A fundamental challenge in developing brain machine interfaces (BMIs) is building a decoder between patterns of brain activity and movement in patients with spinal cord injury, ALS, and amput...
Gilles de la Tourette syndrome (GTS) is a neurodevelopmental disorder exhibiting both motor and behavioral impairment. Like most neuropsychiatric disorders, its pathophysiology has yet to be...
Basal forebrain cholinergic inputs to the cortex are known to contribute to attentional performance. A major focus of my laboratory has been to study the receptors mediating the effects of ac...
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