Cell Signaling/Transduction: part of any communication process that governs basic activities of cells and coordinates all cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis.
In this presentation, Arvid Carlsson, who was awarded the Nobel prize in 2000 for his discovery of the transmitter role of dopamine, will be interviewed by Elias Eriksson. The following aspec...
Impulse control disorders (ICDs), also known as behavioural addictions, are common in the general population and can have marked consequences. ICDs can also commonly occur with exposure...
Traditional models of basal ganglia disorders are grounded in the assumption that network dysfunction is driven by alterations in intrinsic excitability of striatal neurons. Recent work has c...
This talk will provide an overview of Fourier Transform InfraRed (FTIR) chemical imaging as a powerful and versatile method for obtaining information about CNS tissues. By combining imaging a...
In the adult central nervous system (CNS) small populations of neurons are formed in the adult olfactory bulb and dentate gyrus of the hippocampus. In the adult hippocampus, newly born neuron...
Innovation in Psychopharmacology is Dead. Long Live Innovation in Psychopharmacology! What’s going on in our field? Priorities of Big Pharma shifting away fr...
We routinely face decisions requiring evaluation and choice of different actions may or may not yield different types of rewards. These situations trigger competitive decision biases that ref...
Optogenetics or optophysiology is a rapidly growing technique used across an ever broadening array of research fields. Investigators now genetically modify many signalling pathway elements to...
Our goal - To Understand the Neurobiology of Emotions and Affect and Its Relevance to Psychiatric Disorders. This includes: Understanding basic mechanisms of affect, stre...
The NIH BRAIN initiative, informed by the report from the scientific community (BRAIN 2025) is underway. The major funded efforts at this time fit into 3 main categories; 1) defining the comp...
DARPA’s investments aim to leverage brain-function research to alleviate the burden of illness and injury and provide novel, neurotechnology-based capabilities for military personnel an...
Behaviors are motivated by two emotional valences: Seeking pleasure and avoiding pain. The ability to select appropriate behavioral responses to environmental stimuli, such as avoiding a pred...
There is growing interest internationally in elucidating the clinical and biological profile of those at high genetic risk to bipolar disorder (BD) so as to enable the development of targeted...
Since the discovery and maturing of in vitro techniques that characterized neurotransmitter receptor systems in animal and human brain and subsequent development of in vitro and in vivo autor...
Impulsivity can be defined as the tendency to act prematurely without foresight. Behavioural and neurobiological analysis of this construct, based on evidence from both animal and human studi...
Traditional psychiatric textbooks describe schizophrenia as a clinical enigma of unknown aetiology. However, this is no longer true. We now know a great deal about the risk factors, or contr...
This presentation will include both preclinical and small clinical studies with details on mechanism of action, safety and efficacy of a candidate drug that has the capability of alleviating...
Recent advances in noninvasive neuroimaging have set the stage for the systematic exploration of human brain circuits in health and disease. The Human Connectome Project (HCP) is systematical...
At the cellular and molecular levels of operation, neurons and their circuits achieve brain functions by chemical signals, in which the principle agents, neurotransmitters convey the signal f...
The hippocampal formation is one of the most extensively studied regions of the brain, with well described anatomy and basic physiology; moreover, aspects of human memory mediated by hippocam...
Schizophrenia is a severe psychiatric disorder affecting 1% of the world’s population, leading to high human, social and economic burdens. Understanding how the interaction of gene and...
The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative has the ambitious goal of elucidating how neuronal ensembles interactively encode higher brain processes....
The dorsal anterior cingulate cortex (dACC), orbitofrontal cortex (OFC), ventrolateral and ventromedial prefrontal cortex (vlPFC, vmPFC) and their connections with the basal ganglia play a ce...
The dopamine-containing neurons of the midbrain have been implicated in a broad array of psychiatric disorders, ranging from schizophrenia to drug abuse and depression. However, studies seem...
In this presentation, Arvid Carlsson, who was awarded the Nobel prize in 2000 for his discovery of the transmitter role of dopamine, will be interviewed by Elias Eriksson. The following aspec...
Impulse control disorders (ICDs), also known as behavioural addictions, are common in the general population and can have marked consequences. ICDs can also commonly occur with exposure...
Traditional models of basal ganglia disorders are grounded in the assumption that network dysfunction is driven by alterations in intrinsic excitability of striatal neurons. Recent work has c...
This talk will provide an overview of Fourier Transform InfraRed (FTIR) chemical imaging as a powerful and versatile method for obtaining information about CNS tissues. By combining imaging a...
In the adult central nervous system (CNS) small populations of neurons are formed in the adult olfactory bulb and dentate gyrus of the hippocampus. In the adult hippocampus, newly born neuron...
Innovation in Psychopharmacology is Dead. Long Live Innovation in Psychopharmacology! What’s going on in our field? Priorities of Big Pharma shifting away fr...
We routinely face decisions requiring evaluation and choice of different actions may or may not yield different types of rewards. These situations trigger competitive decision biases that ref...
Optogenetics or optophysiology is a rapidly growing technique used across an ever broadening array of research fields. Investigators now genetically modify many signalling pathway elements to...
Our goal - To Understand the Neurobiology of Emotions and Affect and Its Relevance to Psychiatric Disorders. This includes: Understanding basic mechanisms of affect, stre...
The NIH BRAIN initiative, informed by the report from the scientific community (BRAIN 2025) is underway. The major funded efforts at this time fit into 3 main categories; 1) defining the comp...
DARPA’s investments aim to leverage brain-function research to alleviate the burden of illness and injury and provide novel, neurotechnology-based capabilities for military personnel an...
Behaviors are motivated by two emotional valences: Seeking pleasure and avoiding pain. The ability to select appropriate behavioral responses to environmental stimuli, such as avoiding a pred...
There is growing interest internationally in elucidating the clinical and biological profile of those at high genetic risk to bipolar disorder (BD) so as to enable the development of targeted...
Since the discovery and maturing of in vitro techniques that characterized neurotransmitter receptor systems in animal and human brain and subsequent development of in vitro and in vivo autor...
Impulsivity can be defined as the tendency to act prematurely without foresight. Behavioural and neurobiological analysis of this construct, based on evidence from both animal and human studi...
Traditional psychiatric textbooks describe schizophrenia as a clinical enigma of unknown aetiology. However, this is no longer true. We now know a great deal about the risk factors, or contr...
This presentation will include both preclinical and small clinical studies with details on mechanism of action, safety and efficacy of a candidate drug that has the capability of alleviating...
Recent advances in noninvasive neuroimaging have set the stage for the systematic exploration of human brain circuits in health and disease. The Human Connectome Project (HCP) is systematical...
At the cellular and molecular levels of operation, neurons and their circuits achieve brain functions by chemical signals, in which the principle agents, neurotransmitters convey the signal f...
The hippocampal formation is one of the most extensively studied regions of the brain, with well described anatomy and basic physiology; moreover, aspects of human memory mediated by hippocam...
Schizophrenia is a severe psychiatric disorder affecting 1% of the world’s population, leading to high human, social and economic burdens. Understanding how the interaction of gene and...
The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative has the ambitious goal of elucidating how neuronal ensembles interactively encode higher brain processes....
The dorsal anterior cingulate cortex (dACC), orbitofrontal cortex (OFC), ventrolateral and ventromedial prefrontal cortex (vlPFC, vmPFC) and their connections with the basal ganglia play a ce...
The dopamine-containing neurons of the midbrain have been implicated in a broad array of psychiatric disorders, ranging from schizophrenia to drug abuse and depression. However, studies seem...