In a clinical laboratory, tests are done on patient specimens, such as blood, biopsies, and other bodily fluids, to gather information regarding the general health, aiding in diagnosis and potential treatment or disease prevention.
“The poor translatability of early-stage preclinical models is a major setback in oncology drug development. Immortalized cell lines, that are extensively used in drug screens, undergo...
I describe a framework for improving the targeting and precision of transcranial magnetic stimulation (TMS), a noninvasive brain stimulation technique used for research and clinical applicat...
Brain machine interfaces or neural prosthetics have the potential to restore movement to people with paralysis or amputation, bridging gaps in the nervous system with an artificial device. M...
Normal behavior in any moving animal, including humans, relies on communication between motor systems that control movements, and the sensory systems we use to guide these actions. A critica...
Early phase clinical trials investigating novel applications of neural devices, such as deep brain stimulation (DBS) devices, pose ethical challenge during the recruitment of human subjects...
Recent technological advancements in neuroprosthetics allow for wireless recording and stimulation of brain activity in freely moving human participants. At the same time, advancements in vi...
The OrganoPlate is a microtiterplate based Organ-on-a-Chip platform for high throughput drug safety and efficacy screening. It contains up to 96 cell culture chambers that allow co-culture o...
The use of primary cells in vitro is compromised by the limited quantity of cells that can be isolated from one donor, a lack of or very restricted proliferation capacity (e.g. hepatocytes)...
Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease in developed countries, and it affects over 25% of the population worldwide. Within the next five y...
Chaperone networks are dysregulated with aging, but whether compromised Hsp70/Hsp90 chaperone function disturbs neuronal resilience is unknown. Stress‐inducible phosphoprotein 1 (STI1; STIP1...
Open Science has changed research by making data accessible and shareable, contributing to replicability to accelerate and disseminate knowledge. However, for rodent cognitive studies the av...
Misfolded and accumulated neurodegenerative disease associated proteins (NDAPs, such as tau and alpha-synuclein) represent the major pathological hallmark in Alzheimer’s and Parkinson&...
The liver plays a critical role in the metabolism and clearance of more than 70% of marketed drugs. Furthermore, toxicity to the liver is a major reason for preclinical and clinical drug fai...
With an increasing push to improve safety, efficacy, and efficiency throughout the drug development pipeline, researchers are evermore looking to improve the predictive capacity of their in...
DATE: December 18, 2019TIME: 10:00am PSTDavid is the Product Marketing Manager for Biosafety Cabinets at Labconco Corporation (Kansas City, MO). For several years, David has been involv...
DATE: December 17, 2019TIME: 9:00am PST, 12:00pm EST Purpose: Liver x receptors (LXRs) are hypothesized to serve as a link between lipid metabolism and inflammation by prom...
DATE: December 17, 2019TIME: 8:00am PSTMass cytometry instruments simultaneously measure >50 cellular features, with a typical experiment including millions of cells. Dysregulated...
DATE: December 17, 2019 TIME: 2:00pm SGT From WHO 2017 Hepatitis report, an estimated 290 million (89%) of the 325 million people living with viral hepatitis B and C are unaware that they ar...
DATE: December 12, 2019TIME: 11:00am PST Primary immunodeficiency disorders continue to have delayed diagnoses and are commonly under diagnosed. Differentiating betw...
DATE: December 12, 2019 TIME: 8:00am PST La infección por el virus del papiloma humano (VPH) es el causante principal de cáncer de cuello uterino. Los tipos 16 y 18 del VPH son...
DATE: December 11, 2019 TIME: 8:00am PST, 11:00am EST, 4:00pm GMT The Zimmerwald Laser and Astrometric Telescope (ZIMLAT) is the most versatile instrument of the Swiss Optical Ground Stati...
DATE: December 11, 2019TIME: 7:00am PST, 10:00am EST An important part of the biopharma industry, Plasmid DNA is used as a gene-delivery vehicle for DNA vaccination and as a key...
“The poor translatability of early-stage preclinical models is a major setback in oncology drug development. Immortalized cell lines, that are extensively used in drug screens, undergo...
I describe a framework for improving the targeting and precision of transcranial magnetic stimulation (TMS), a noninvasive brain stimulation technique used for research and clinical applicat...
Brain machine interfaces or neural prosthetics have the potential to restore movement to people with paralysis or amputation, bridging gaps in the nervous system with an artificial device. M...
Normal behavior in any moving animal, including humans, relies on communication between motor systems that control movements, and the sensory systems we use to guide these actions. A critica...
Early phase clinical trials investigating novel applications of neural devices, such as deep brain stimulation (DBS) devices, pose ethical challenge during the recruitment of human subjects...
Recent technological advancements in neuroprosthetics allow for wireless recording and stimulation of brain activity in freely moving human participants. At the same time, advancements in vi...
The OrganoPlate is a microtiterplate based Organ-on-a-Chip platform for high throughput drug safety and efficacy screening. It contains up to 96 cell culture chambers that allow co-culture o...
The use of primary cells in vitro is compromised by the limited quantity of cells that can be isolated from one donor, a lack of or very restricted proliferation capacity (e.g. hepatocytes)...
Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease in developed countries, and it affects over 25% of the population worldwide. Within the next five y...
Chaperone networks are dysregulated with aging, but whether compromised Hsp70/Hsp90 chaperone function disturbs neuronal resilience is unknown. Stress‐inducible phosphoprotein 1 (STI1; STIP1...
Open Science has changed research by making data accessible and shareable, contributing to replicability to accelerate and disseminate knowledge. However, for rodent cognitive studies the av...
Misfolded and accumulated neurodegenerative disease associated proteins (NDAPs, such as tau and alpha-synuclein) represent the major pathological hallmark in Alzheimer’s and Parkinson&...
The liver plays a critical role in the metabolism and clearance of more than 70% of marketed drugs. Furthermore, toxicity to the liver is a major reason for preclinical and clinical drug fai...
With an increasing push to improve safety, efficacy, and efficiency throughout the drug development pipeline, researchers are evermore looking to improve the predictive capacity of their in...
DATE: December 18, 2019TIME: 10:00am PSTDavid is the Product Marketing Manager for Biosafety Cabinets at Labconco Corporation (Kansas City, MO). For several years, David has been involv...
DATE: December 17, 2019TIME: 9:00am PST, 12:00pm EST Purpose: Liver x receptors (LXRs) are hypothesized to serve as a link between lipid metabolism and inflammation by prom...
DATE: December 17, 2019TIME: 8:00am PSTMass cytometry instruments simultaneously measure >50 cellular features, with a typical experiment including millions of cells. Dysregulated...
DATE: December 17, 2019 TIME: 2:00pm SGT From WHO 2017 Hepatitis report, an estimated 290 million (89%) of the 325 million people living with viral hepatitis B and C are unaware that they ar...
DATE: December 12, 2019TIME: 11:00am PST Primary immunodeficiency disorders continue to have delayed diagnoses and are commonly under diagnosed. Differentiating betw...
DATE: December 12, 2019 TIME: 8:00am PST La infección por el virus del papiloma humano (VPH) es el causante principal de cáncer de cuello uterino. Los tipos 16 y 18 del VPH son...
DATE: December 11, 2019 TIME: 8:00am PST, 11:00am EST, 4:00pm GMT The Zimmerwald Laser and Astrometric Telescope (ZIMLAT) is the most versatile instrument of the Swiss Optical Ground Stati...
DATE: December 11, 2019TIME: 7:00am PST, 10:00am EST An important part of the biopharma industry, Plasmid DNA is used as a gene-delivery vehicle for DNA vaccination and as a key...
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