In a clinical laboratory, tests are done on patient specimens, such as blood, biopsies, and other bodily fluids, to gather information regarding the general health, aiding in diagnosis and potential treatment or disease prevention.
Next-generation sequencing (NGS) technologies are powerful approaches for diagnosis and surveillance of emerging infections. Unbiased metagenomic NGS can detect the full spectrum of pathogen...
Natural preservation is often cited as effective and “safe” alternative to traditional synthetic preservative systems. However, the so-called natural preservatives bring a number...
Respiratory viral infections remain a leading cause of medical visits and can contribute significantly to morbidity and mortality. Influenza, together with pneumonia, is the leading infectio...
Analytical ultracentrifugation (AUC) is a powerful technique for analyzing fundamental characteristics of macromolecules in solution, including size and shape, assembly state, and degree of p...
Exosomes are small secreted vesicles that have a diameter of ~50-200 nm. Exosomes are enriched for a specific subset of host-derived proteins, nucleic acids, lipids and carbohydrates, though ...
Date: Tuesday, June 30th, 2015Time: 11:00AM PDT, 2:00PM EDT There is a growing interest of LC-tandem MS in clinical laboratories because this analytical technique can provide definitive ident...
The emerging field of RNA nanotechnology has led to the utilization of the platform in the field of bionanotechnology as sensing platforms, diverse nanoparticle construction, in vivo computin...
Clinical laboratories and, indeed, health care overall, are facing potential paradigm shifts in how innovative and higher quality care are delivered to patients. From ever more precise and ac...
Consistent accuracy in reporting quantitative viral load results is critically important to patients, their physicians and to the clinical laboratory. In clinical practice, quantitative viral...
Errors in healthcare can have catastrophic results for patients. Work settings with a strong interdisciplinary teamwork culture can decrease the opportunities for errors to occur. Teamwork co...
Matching the mutational profile of a patient's tumor with appropriate targeted agents is a goal of personalized medicine in oncology. The number of FDA-approved targeted therapies, as well as...
Appropriate utilization of laboratory testing is important for the quality and safety in the healthcare system and to assist in the control of unnecessary costs in the healthcare system. Per...
When a patient presents with acute bloody diarrhea and tests negative for common causes such as campylobacter and salmonella, what's missing? Shiga toxin-producing E. coli (STEC) is increasin...
CMS continues to make changes to how all healthcare providers are reimbursed in attempts to control the cost of the services provided to Medicare beneficiaries. This has led to value-based r...
The practice of laboratory clinical microbiology is finally changing driven by the assimilation of newer technologies, like Matrix Assisted Laser Desorption Ionization - Time of Flight/Mass S...
Carbapenemase-producing Gram-Negative Bacilli are the latest public health threat, spreading rapidly across the globe in the last decade. The Chicago region has experienced a growing outbrea...
Review of recent, post ACA, health care legislation for impact on physicians and clinical laboratories. Overview of possible new health care legislation and update on Medicare regulatory act...
With the development of the XLA/XLI analytical ultracentrifuges and their exquisitely sensitive optics that can accurately detect absorbance signals in the range of 0.005 A to 1.5 A. and diff...
Germline cancer genetics became a reality with the cloning of the tumor suppressor gene RB1 for hereditary retinoblastoma in 1986 by Friend and Weinberg. The existence of cancer susceptibili...
With current NGS platforms, the boundaries of variant detection and gene content for genetic disease panels has been vastly expanded leading to increases in detection rates. However these pla...
I will discuss the use of genomic technologies - mostly ultrahigh-throughput DNA sequencing - to study normal human biology and to determine what goes wrong when we have disease. First I wil...
The implementation of Next Generation Sequencing (NGS) technology in the clinical laboratory has allowed for large-scale panel testing of many genes simultaneously at a reduced cost and turn-...
Extracellular vesicles (EVs) include the exosomes (30-100 nm) that are produced through the endocytic pathway via the multivesicular bodies and the ectosomes (100-1000 nm) that are released t...
Next-generation sequencing (NGS) technologies are powerful approaches for diagnosis and surveillance of emerging infections. Unbiased metagenomic NGS can detect the full spectrum of pathogen...
Natural preservation is often cited as effective and “safe” alternative to traditional synthetic preservative systems. However, the so-called natural preservatives bring a number...
Respiratory viral infections remain a leading cause of medical visits and can contribute significantly to morbidity and mortality. Influenza, together with pneumonia, is the leading infectio...
Analytical ultracentrifugation (AUC) is a powerful technique for analyzing fundamental characteristics of macromolecules in solution, including size and shape, assembly state, and degree of p...
Exosomes are small secreted vesicles that have a diameter of ~50-200 nm. Exosomes are enriched for a specific subset of host-derived proteins, nucleic acids, lipids and carbohydrates, though ...
Date: Tuesday, June 30th, 2015Time: 11:00AM PDT, 2:00PM EDT There is a growing interest of LC-tandem MS in clinical laboratories because this analytical technique can provide definitive ident...
The emerging field of RNA nanotechnology has led to the utilization of the platform in the field of bionanotechnology as sensing platforms, diverse nanoparticle construction, in vivo computin...
Clinical laboratories and, indeed, health care overall, are facing potential paradigm shifts in how innovative and higher quality care are delivered to patients. From ever more precise and ac...
Consistent accuracy in reporting quantitative viral load results is critically important to patients, their physicians and to the clinical laboratory. In clinical practice, quantitative viral...
Errors in healthcare can have catastrophic results for patients. Work settings with a strong interdisciplinary teamwork culture can decrease the opportunities for errors to occur. Teamwork co...
Matching the mutational profile of a patient's tumor with appropriate targeted agents is a goal of personalized medicine in oncology. The number of FDA-approved targeted therapies, as well as...
Appropriate utilization of laboratory testing is important for the quality and safety in the healthcare system and to assist in the control of unnecessary costs in the healthcare system. Per...
When a patient presents with acute bloody diarrhea and tests negative for common causes such as campylobacter and salmonella, what's missing? Shiga toxin-producing E. coli (STEC) is increasin...
CMS continues to make changes to how all healthcare providers are reimbursed in attempts to control the cost of the services provided to Medicare beneficiaries. This has led to value-based r...
The practice of laboratory clinical microbiology is finally changing driven by the assimilation of newer technologies, like Matrix Assisted Laser Desorption Ionization - Time of Flight/Mass S...
Carbapenemase-producing Gram-Negative Bacilli are the latest public health threat, spreading rapidly across the globe in the last decade. The Chicago region has experienced a growing outbrea...
Review of recent, post ACA, health care legislation for impact on physicians and clinical laboratories. Overview of possible new health care legislation and update on Medicare regulatory act...
With the development of the XLA/XLI analytical ultracentrifuges and their exquisitely sensitive optics that can accurately detect absorbance signals in the range of 0.005 A to 1.5 A. and diff...
Germline cancer genetics became a reality with the cloning of the tumor suppressor gene RB1 for hereditary retinoblastoma in 1986 by Friend and Weinberg. The existence of cancer susceptibili...
With current NGS platforms, the boundaries of variant detection and gene content for genetic disease panels has been vastly expanded leading to increases in detection rates. However these pla...
I will discuss the use of genomic technologies - mostly ultrahigh-throughput DNA sequencing - to study normal human biology and to determine what goes wrong when we have disease. First I wil...
The implementation of Next Generation Sequencing (NGS) technology in the clinical laboratory has allowed for large-scale panel testing of many genes simultaneously at a reduced cost and turn-...
Extracellular vesicles (EVs) include the exosomes (30-100 nm) that are produced through the endocytic pathway via the multivesicular bodies and the ectosomes (100-1000 nm) that are released t...
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