Digital Biology: the study of the fundamental computation performed by biological processes, from gene regulatory systems to ecosystems and from neural networks to swarming systems. The increasing amount of data that are being acquired, stored, and processed in the life sciences and health sector makes the development of new information technologies one of the key factors for advancing the current state of knowledge in biomedical and health research.
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Understanding morphogenesis is an inherently four-dimensional problem, as cells change position in space and the embryo is transformed over time. Dorsal intercalation of epidermal cells in t...
The current gold standard for COVID-19 diagnosis is based on the detection of SARS-CoV-2 nucleic acid using real-time quantitative PCR (RT-qPCR). Recent studies suggest limitations of RT-qPC...
Targeted therapies for cancer are increasingly being developed as an alternative for, and in addition to, immunotherapy. Altered tumor signaling can be exploited to single-out cancer cells f...
While many technologies focus on either exploring the spatial context of a handful of targets, or expression patterns of hundreds or thousands of targets in bulk samples or dissociated singl...
Background: Growing evidence supports the critical role of preexisting immune response in triple negative breast cancer (TNBC). However, there are limitations with current evaluation approac...