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Disease Modeling
Disease modeling is the use of a disease model, which is an animal or cells containing all or some of the pathological characteristics and mechanisms of a disease, to study that particular disease.
MAY 20, 2020 | 1:15 PM
Background: Acute myeloid leukemia (AML) is a molecularly and clinically heterogeneous hematological malignancy. Despite recent advancements in the treatment of AML, approximately 50% of pat...
MAY 20, 2020 | 11:15 AM
Background: CDK4/6 inhibitors increase tumor immunogenicity in preclinical models of breast cancer and several trials combining CDK4/6 inhibitors and anti-PD1/PDL1 therapies are underway. Ho...
MAY 20, 2020 | 12:00 AM
The basic units of biological structure and function are cells, which exhibit wide variation in regard to both type and state. We assess such variation by simultaneously profiling the transc...
MAY 19, 2020 | 1:15 PM
Pancreatic Ductal Adenocarcinoma (PDAC) is a highly aggressive disease associated with poor outcome. It is expected to be the leading cause of cancer-related death in 2030. The unique microe...
MAY 14, 2020 | 12:00 AM
The ability to rapidly and accurately identify pain in mice is critical for providing them optimal care and welfare. To meet this need, we developed and validated the Grooming Transfer Test...
MAY 14, 2020 | 12:00 AM
Experimental models that promise to replace animal tests that are currently required for drugs and chemicals are rapidly proliferating. This includes a number of novel solutions offered by b...
MAY 13, 2020 | 7:00 AM
DATE: May 13, 2020 TIME: 7am PT, 10am ET, 4pm CEST Stem cells represent an important tool in a wide range of applications, including basic research, disease modeling, drug discovery, and reg...
MAY 12, 2020 | 9:00 AM
NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
MAY 12, 2020 | 8:00 AM
DATE: May 12, 2020 TIME: 8:00am PT Idiopathic aplastic anemia (AA) has two key characteristics: an autoimmune response against hematopoietic stem/progenitor cells and regulatory T cells (Tre...
MAY 08, 2020 | 10:00 AM
DATE: May 8, 2020 TIME: 10:00am PT, 11:00am MT, 1:00pm ET The application of next generation sequencing to interrogate immune repertoires and methods in which these highly complex dataset...
APR 30, 2020 | 7:00 AM
DATE: April 30, 2020 TIME: 7am PT, 10am ET, 4pm CEST Aged more than one century, nucleic acid purification is anything but ordinary. Nucleic Acid Purification, also termed Nucleic Acid Extra...
