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Drug Development
Drug development: describes the process of developing a new drug that energetically targets a specific weakness in a cell. The process consist of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery.
JAN 31, 2019 | 10:30 AM
The Strep-Tactin®XT:Twin-Strep-tag®-purification system enables protein purification at high yields and purity under physiological conditions. Providing the highest binding affinity a...
JAN 31, 2019 | 9:00 AM
The biologics development process is fraught with risks from pre-clinical studies through clinical evaluation. Prominent among these risks are changes in the critical quality attributes of th...
JAN 31, 2019 | 7:30 AM
Prodrugs are harmless in their native state, as they are not targeted by human enzymes. But they can be converted into highly toxic compounds (the “drug”) by viral or bacterial en...
JAN 31, 2019 | 6:00 AM
Ambrx’s mammalian expression platform (EuCODE™) enables non-native amino acids (nnAAs) through an expanded genetic code to both generate novel bio-therapeutics and to optimize the...
JAN 29, 2019 | 9:00 AM
DATE: January 29. 2019TIME: 09:00am PST, 12:00pm EST In healthy tissue, a reservoir of stem cells gives rise to non-stem cells while simul...
JAN 15, 2019 | 12:00 AM
DATE: January 15, 2018TIME: 4:00pm SGTPThere is a clear call to automate manufacturing for cell and gene therapy products, but when should you automate? In this session, we...
DEC 10, 2018 | 10:00 PM
DATE: December 11, 2018TIME: 06:00 PSTIt’s understood and accepted that animal disease models generally offer great value for pre-clinical research and efficient drug screeni...
DEC 06, 2018 | 8:00 AM
DATE: December 6, 2018TIME: 11:00am EST, 5:00pm CET Introduction Micro-computed tomography (micro-CT) offers significant advantages o...
DEC 06, 2018 | 1:00 AM
DATE: December 6, 2018TIME: 10:00am CET, 5:00pm CST Intro Micro-computed tomography (micro-CT) offers significant advantage...
DEC 03, 2018 | 11:00 PM
DATE: December 4, 2018TIME: 8:00am CET PSCs represent an important tool in a wide range of applications, including basic research, disease...
NOV 21, 2018 | 9:00 AM
DATE: November 21,2018TIME: 09:00am PST, 12:00pm EST Vaginal infections are a source of considerable morbidity among women. It is estimated that there are more than 10...
NOV 15, 2018 | 12:00 PM
Drug overdose surpassed motor vehicle accidents as the leading cause of accidental death 2006 and has remained the leading cause of accidental death at the state and national level. Mos...
NOV 15, 2018 | 10:00 AM
DATE: November 15, 2018TIME: 10:00am PT, 1:00pm ET Multiplex fluorescence immunohistochemistry offers a window into the biology of human disease, enabling the ana...
NOV 15, 2018 | 10:00 AM
The complexity of the human brain, with thousands of neuronal types, permits the development of sophisticated behavioral repertoires, such as language, tool use, self-awareness, symbolic thou...
NOV 15, 2018 | 9:00 AM
Watch how to passage feeder-free Pluripotent Stem Cells (PSCs) cultured in Essential 8 medium using EDTA. Learn the best practices to help ensure successful passage of your cells....
NOV 15, 2018 | 8:00 AM
CRISPR ribonucleoproteins (RNPs) can generate programmable gene edits, however imprecise editing and efficient delivery to human stem cells are key challenges. Here we describe novel biochemi...
NOV 15, 2018 | 7:00 AM
The use of human pluripotent stem cells (hPSCs) for in vitro disease-modeling is limited by the lack of robust and efficient protocols for the differentiation of relevant adult cell types. Pr...
NOV 15, 2018 | 4:00 AM
Development of physiologically relevant cellular models, with strong translatability to human pathophysiology, is critical for identification and validation of novel therapeutic targets. Cell...
NOV 14, 2018 | 3:00 PM
Neuronal migration defects, including pachygyria, are among the most severe developmental brain defects in humans. Using human genetics approaches, we recently identified bi-allelic truncatin...
NOV 14, 2018 | 9:00 AM
With significant decrease in the cost of sequencing in numerous commercial as well as cancer center–driven initiatives, genomic profiling is increasingly becoming routine across multipl...
NOV 13, 2018 | 9:00 AM
DATE: November 13, 2018TIME: 9:00am PST, 12:00pm ESTExtracellular vesicles (EVs) are cell-secreted nanoparticles that play a pivotal role in intercellular communic...
NOV 07, 2018 | 8:00 PM
DATE: November 7, 2018TIME: 8:00PM PSTExosomes have been shown to have significant roles in cancer including disease progression acting in the tumor micro-environment, metasta...
NOV 07, 2018 | 7:00 AM
DATE: November 7, 2018TIME: 7:00AM PDTExosomes have been shown to have significant roles in cancer including disease progression acting in the tumor micro-environment, metastasis a...