Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.
Here we present a case study on the combined use of cannabis, psilocybin, and conventional oncology treatments which induced remission in a stage IV metastatic breast cancer patient. A 49-ye...
Given that the hemp industry in the United States is still nascent, certified seed offers American farmers a way to minimize the risk of growing hemp. For hemp, certification carries additio...
In the post prohibition era, a vacuum of regulations, standards, and best practices is quickly being filled. Learn how those who truly care about the cannabis industry are acting through exi...
Explore the world of the vaping through a presentation whereas science, politics, and culture collide. Dr. Marcu guides you through a nuanced discussion of why the vaping crisis curve seems...
With the passing of the 2018 Farm Bill legalizing hemp, farmers are allowed to grow hemp. Like any other agricultural crop, pesticides are applied to hemp plants to protect it from pests and...
The objective of this study was to produce a fast, accurate, and precise method for analyzing terpenes in hemp using headspace/gas chromatography/mass spectrometry. Modern interest in terpen...
Healthcare providers are increasingly being asked from their patients for advice and recommendations for the use of cannabis in all types of conditions and disease states. One of the most ch...
Every cannabis variety has unique genetics, but the plant's potential is limited by its environment. Manipulating inputs and modifying the environment is the most effective way to maximi...
Vaporizing cannabis concentrates is increasing in popularity as a potentially healthier alternative to smoking. However, little is known about the chemical profiles of aerosolized concentrat...
DATE: March 24, 2020 TIME: 10:00 am PDT, 1:00pm EDT The Clampfit software module is a useful tool to manipulate and analyze electrophysiological data acquired by pCLAMP™ software. Rece...
Whether you are performing killing assays, characterizing the tumor microenvironment, or investigating immunogenicity, primary cells are essential for the discovery of new therapeutics. Conc...
Digital spatial profiling (DSP) on the NanoString GeoMx platform enables high plex molecular profiling of clinical tissue samples. This new profiling strategy enables deep insights into the...
QIAGEN CLC Genomics Workbench is a powerful solution to analyze and visualize next generation sequencing (NGS) data. Powered by cutting-edge technology and accelerated algorithms, it support...
CRISPR revolutionized gene editing, but multi-target screening remains a complex goal. In addition, the fast pace of CRISPR technology development has brought sophisticated options for libra...
Recent advances in DNA sequencing and omics-based capabilities are revealing incredible therapeutic opportunities and quickly transforming drug discovery. Molecularly targeted drugs aim to e...
Centhaquine (previously used names, centhaquin and PMZ-2010; International Non-proprietary Name (INN) recently approved by WHO is centhaquine) is being developed by us as a first-in-class re...
Learn about how to generate a small scale CAR-T workflow using ThermoFisher products See detailed characterization tools that can be utilized and applied in a CAR-T workflow...
The compendium of newly emerging and currently available hemophilia and anticoagulant treatments, while offering new choices for improved patient care, can create significant levels of inter...
DATE: January 14, 2019 TIME: 8:00am PST Drug-induced QT interval prolongation and Torsades de Pointes (TdP) arrhythmias are the leading causes for drug withdrawals from market and compound a...
“The poor translatability of early-stage preclinical models is a major setback in oncology drug development. Immortalized cell lines, that are extensively used in drug screens, undergo...
Biomarkers are critical tools for all stages of cancer research, from drug development through clinical applications. Cancer is fundamentally a disease of unregulated cell growth and circumv...
Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
The use of primary cells in vitro is compromised by the limited quantity of cells that can be isolated from one donor, a lack of or very restricted proliferation capacity (e.g. hepatocytes)...
Here we present a case study on the combined use of cannabis, psilocybin, and conventional oncology treatments which induced remission in a stage IV metastatic breast cancer patient. A 49-ye...
Given that the hemp industry in the United States is still nascent, certified seed offers American farmers a way to minimize the risk of growing hemp. For hemp, certification carries additio...
In the post prohibition era, a vacuum of regulations, standards, and best practices is quickly being filled. Learn how those who truly care about the cannabis industry are acting through exi...
Explore the world of the vaping through a presentation whereas science, politics, and culture collide. Dr. Marcu guides you through a nuanced discussion of why the vaping crisis curve seems...
With the passing of the 2018 Farm Bill legalizing hemp, farmers are allowed to grow hemp. Like any other agricultural crop, pesticides are applied to hemp plants to protect it from pests and...
The objective of this study was to produce a fast, accurate, and precise method for analyzing terpenes in hemp using headspace/gas chromatography/mass spectrometry. Modern interest in terpen...
Healthcare providers are increasingly being asked from their patients for advice and recommendations for the use of cannabis in all types of conditions and disease states. One of the most ch...
Every cannabis variety has unique genetics, but the plant's potential is limited by its environment. Manipulating inputs and modifying the environment is the most effective way to maximi...
Vaporizing cannabis concentrates is increasing in popularity as a potentially healthier alternative to smoking. However, little is known about the chemical profiles of aerosolized concentrat...
DATE: March 24, 2020 TIME: 10:00 am PDT, 1:00pm EDT The Clampfit software module is a useful tool to manipulate and analyze electrophysiological data acquired by pCLAMP™ software. Rece...
Whether you are performing killing assays, characterizing the tumor microenvironment, or investigating immunogenicity, primary cells are essential for the discovery of new therapeutics. Conc...
Digital spatial profiling (DSP) on the NanoString GeoMx platform enables high plex molecular profiling of clinical tissue samples. This new profiling strategy enables deep insights into the...
QIAGEN CLC Genomics Workbench is a powerful solution to analyze and visualize next generation sequencing (NGS) data. Powered by cutting-edge technology and accelerated algorithms, it support...
CRISPR revolutionized gene editing, but multi-target screening remains a complex goal. In addition, the fast pace of CRISPR technology development has brought sophisticated options for libra...
Recent advances in DNA sequencing and omics-based capabilities are revealing incredible therapeutic opportunities and quickly transforming drug discovery. Molecularly targeted drugs aim to e...
Centhaquine (previously used names, centhaquin and PMZ-2010; International Non-proprietary Name (INN) recently approved by WHO is centhaquine) is being developed by us as a first-in-class re...
Learn about how to generate a small scale CAR-T workflow using ThermoFisher products See detailed characterization tools that can be utilized and applied in a CAR-T workflow...
The compendium of newly emerging and currently available hemophilia and anticoagulant treatments, while offering new choices for improved patient care, can create significant levels of inter...
DATE: January 14, 2019 TIME: 8:00am PST Drug-induced QT interval prolongation and Torsades de Pointes (TdP) arrhythmias are the leading causes for drug withdrawals from market and compound a...
“The poor translatability of early-stage preclinical models is a major setback in oncology drug development. Immortalized cell lines, that are extensively used in drug screens, undergo...
Biomarkers are critical tools for all stages of cancer research, from drug development through clinical applications. Cancer is fundamentally a disease of unregulated cell growth and circumv...
Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
The use of primary cells in vitro is compromised by the limited quantity of cells that can be isolated from one donor, a lack of or very restricted proliferation capacity (e.g. hepatocytes)...