Fundamental research, in comparison to applied research, is an area of scientific research that focuses on progressing rudimentary scientific theories with the goal of further understanding scientific basics and making educated predictions on observed phenomena.
Extrachromosomal circular DNA (eccDNA) comprises products of genomic recombination that cause somatic changes in gene length and sequence. These circular molecules are derived from canonical...
Coordination of immune cell metabolic programs with cell fate and state is a fundamental determinant of immune responses. Emerging evidence highlights that the interplay between immune signa...
Current methods to treat malignant brain tumors are highly intrusive, leading to poor quality of life with abysmal patient survival rates. Combined with radiation therapy, first/second-line...
Metabolic reprogramming is critical for governing proper T cell immune responses, including activation, production of effector molecule, migration and differentiation. The metabolic stress T...
DATE: July 9, 2020 TIME: 2pm SGT, 3pm JST, 4pm AEST Mass Spectrometry (MS) has been an invaluable tool for physicists and basic chemists for over 100 years. It was not until around 30 to 40...
DATE: June 25, 2020 TIME: 8:00am PDT, 11:00am EDT, 4:00pm BST, 5:00pm CEST Mass Spectrometry (MS) has been an invaluable tool for physicists and basic chemists for over 100 years. It was not...
DATE: June 24, 2020 TIME: 10:00am PT Does your work require you to freeze dry samples? Are your results inconsistent? Is your freeze dry cycle taking too long? Learn how to optimize your lyo...
While the introduction of atmospheric pressure ion sources, such as electrospray ionization, revolutionized the field of mass spectrometry it also introduced new instrumental compilations no...
Analysis of antigen- and virus-specific T cells is essential to the understanding of fundamental immunological processes in the contexts of e.g. infectious diseases, immuno-oncology, as well...
Veterinary drugs are commonly used chemicals to improve the growth and health outcomes of farm animals raised for human consumption. However, improper use of vet-drugs in animal farming can...
In 2019, over 220,000 Canadians will be diagnosed with cancer and 82,000 will die of the disease. Approximately 90% of cancer related deaths are the result of metastatic disease. This is ind...
A key step in the clinical production of CAR T cells is the expansion of engineered T cells. To generate enough cells for viable adoptive cell therapy, cells must be robustly stimulated, whi...
DATE: May 27, 2020 TIME: 9:00am PT Analysis of antigen- and virus-specific T cells is essential to the understanding of fundamental immunological processes in the contexts of e.g. infectious...
Techniques to analyze and sort single cells based on secreted products have the potential to transform our understanding of cellular biology as well as accelerate the development of next gen...
The current gold standard for COVID-19 diagnosis is based on the detection of SARS-CoV-2 nucleic acid using real-time quantitative PCR (RT-qPCR). Recent studies suggest limitations of RT-qPC...
Biomedical research suffers from a translation gap, where most treatments that seem effective when tested on animals turn out not to work in human patients. This is likely due in large part...
Our laboratory uses tools from pharmacology, genomics, and cell signaling to identify new precision anticancer therapeutic strategies. Under this broad heading, our work involves three key a...
DATE: April 15, 2020 TIME: 4:00pm CEST, 07:00am PT, 010:00am ET The assessment of cell health and cellular responses after experimental manipulation continue to be a very important aspect of...
DATE: April 1, 2020 TIME: 8:00am PST The capabilities of liquid chromatography coupled to mass spectrometry make the technology a very attractive tool in clinical laboratory settings. Howeve...
Given that the hemp industry in the United States is still nascent, certified seed offers American farmers a way to minimize the risk of growing hemp. For hemp, certification carries additio...
Vaporizing cannabis concentrates is increasing in popularity as a potentially healthier alternative to smoking. However, little is known about the chemical profiles of aerosolized concentrat...
Working memory (the ability to hold some information in mind for a few seconds, and to manipulate that information) and decision-making (committing to one out of multiple possible choices) a...
Learning is often an emotional process. Emotional stimuli with different valences, such as threat and reward, can transform an otherwise neutral sensory input into one that can trigger disti...
The US Brain Research through Advancing Innovative Neurotechnologies is a research program focused on building fundamental knowledge of how brain circuits process information to enable human...
Extrachromosomal circular DNA (eccDNA) comprises products of genomic recombination that cause somatic changes in gene length and sequence. These circular molecules are derived from canonical...
Coordination of immune cell metabolic programs with cell fate and state is a fundamental determinant of immune responses. Emerging evidence highlights that the interplay between immune signa...
Current methods to treat malignant brain tumors are highly intrusive, leading to poor quality of life with abysmal patient survival rates. Combined with radiation therapy, first/second-line...
Metabolic reprogramming is critical for governing proper T cell immune responses, including activation, production of effector molecule, migration and differentiation. The metabolic stress T...
DATE: July 9, 2020 TIME: 2pm SGT, 3pm JST, 4pm AEST Mass Spectrometry (MS) has been an invaluable tool for physicists and basic chemists for over 100 years. It was not until around 30 to 40...
DATE: June 25, 2020 TIME: 8:00am PDT, 11:00am EDT, 4:00pm BST, 5:00pm CEST Mass Spectrometry (MS) has been an invaluable tool for physicists and basic chemists for over 100 years. It was not...
DATE: June 24, 2020 TIME: 10:00am PT Does your work require you to freeze dry samples? Are your results inconsistent? Is your freeze dry cycle taking too long? Learn how to optimize your lyo...
While the introduction of atmospheric pressure ion sources, such as electrospray ionization, revolutionized the field of mass spectrometry it also introduced new instrumental compilations no...
Analysis of antigen- and virus-specific T cells is essential to the understanding of fundamental immunological processes in the contexts of e.g. infectious diseases, immuno-oncology, as well...
Veterinary drugs are commonly used chemicals to improve the growth and health outcomes of farm animals raised for human consumption. However, improper use of vet-drugs in animal farming can...
In 2019, over 220,000 Canadians will be diagnosed with cancer and 82,000 will die of the disease. Approximately 90% of cancer related deaths are the result of metastatic disease. This is ind...
A key step in the clinical production of CAR T cells is the expansion of engineered T cells. To generate enough cells for viable adoptive cell therapy, cells must be robustly stimulated, whi...
DATE: May 27, 2020 TIME: 9:00am PT Analysis of antigen- and virus-specific T cells is essential to the understanding of fundamental immunological processes in the contexts of e.g. infectious...
Techniques to analyze and sort single cells based on secreted products have the potential to transform our understanding of cellular biology as well as accelerate the development of next gen...
The current gold standard for COVID-19 diagnosis is based on the detection of SARS-CoV-2 nucleic acid using real-time quantitative PCR (RT-qPCR). Recent studies suggest limitations of RT-qPC...
Biomedical research suffers from a translation gap, where most treatments that seem effective when tested on animals turn out not to work in human patients. This is likely due in large part...
Our laboratory uses tools from pharmacology, genomics, and cell signaling to identify new precision anticancer therapeutic strategies. Under this broad heading, our work involves three key a...
DATE: April 15, 2020 TIME: 4:00pm CEST, 07:00am PT, 010:00am ET The assessment of cell health and cellular responses after experimental manipulation continue to be a very important aspect of...
DATE: April 1, 2020 TIME: 8:00am PST The capabilities of liquid chromatography coupled to mass spectrometry make the technology a very attractive tool in clinical laboratory settings. Howeve...
Given that the hemp industry in the United States is still nascent, certified seed offers American farmers a way to minimize the risk of growing hemp. For hemp, certification carries additio...
Vaporizing cannabis concentrates is increasing in popularity as a potentially healthier alternative to smoking. However, little is known about the chemical profiles of aerosolized concentrat...
Working memory (the ability to hold some information in mind for a few seconds, and to manipulate that information) and decision-making (committing to one out of multiple possible choices) a...
Learning is often an emotional process. Emotional stimuli with different valences, such as threat and reward, can transform an otherwise neutral sensory input into one that can trigger disti...
The US Brain Research through Advancing Innovative Neurotechnologies is a research program focused on building fundamental knowledge of how brain circuits process information to enable human...
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