Gene Expression: the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as transfer RNA (tRNA) or small nuclear RNA (snRNA) genes, the product is a functional RNA. The process of gene expression is used by all known life-eukaryotes (including multicellular organisms), prokaryotes (bacteria and archaea), and utilized by viruses-to generate the macromolecular machinery for life.
Understanding how genes coordinate their expression across cells in a growing embryo can provide insights into the transcriptional programs that control development. Intercellular variability...
The flexibility of the BioMark Real-Time PCR System, allow us to preform genetic research using different types of nano-fluidic (48.48 or 96.96) chips setup, in the thermal cycle of these chi...
The ENCODE and modENCODE consortia have generated a resource containing large amounts of transcriptomic data, extensive mapping of chromatin states, as well as the binding locations of >30...
As next-generation sequencing (NGS) platforms advance in their speed, ease-of-use, and cost-effectiveness, many translational researchers are transitioning from microarrays to RNA sequencing...
The human genome encodes ~21,500 proteins that are subject to reversible phosphorylation at nearly 1 million phosphosites by about 538 protein kinases and 156 protein phosphatases. Amongst ot...
Down syndrome (DS) is a complex multi-system disorder affecting more than 5.8 million individuals around the world and it causes significant physical, psychological, and cognitive abnormaliti...
Laboratory rats and mice are the most used animal species in scientific research, but still having a lot of information available about them, there are many places in Latin America where ther...
Informatics and internet are widely accepted tools in education and research. In the past decades new teaching and learning strategies have been developed and implemented. E-learning was def...
Intravascular catheterization access for injection and sampling is one of the most common experimental surgical procedures.Catheters and ports have been designed to reduce the problems of occ...
perioperative analgesia aims to minimize, or even eliminate pain during a surgical procedure. Currently this approach is rarely performed using a single analgesic drug and more commonly diff...
The zebrafish, Danio rerio, is an ideal model organism to address a broad array of biomedical questions, and is now widely employed to answer questions about aging, behavior, cancer, growth,...
All trainers are people but not all people are trainers. Several factors beyond the trainer influence the effectiveness of a safety training programs. This program will discuss the critical...
Oftentimes, by the time that laboratory animal facility personnel learn about a facility construction project, the project has been underway for quiet some time without their knowledge but mo...
We all have to provide training; if our program is big or small, a germ-free mouse colony or field studies in Africa, centralized or not. Animal research programs, as varied as they are, have...
The environment in which laboratory rodents are kept has an impact on experimental data and breeding performance. The quality of the environment is defined by both the quality of the primary...
The rise of zebrafish as a research model has been dramatic. Given the global nature of the work, the rise in shipping zebrafish as a laboratory species has been sharp. Up until this point th...
Biofilms, are defined as communities of microorganisms that grow embedded in a self-generated matrix of exopolysaccharides and adhered to an inert surface or a live tissue. They are formed 95...
The proper surgical techniques represent a key opportunity to improve the welfare of laboratory rodents, while meeting legal and ethical obligations. Use of inappropriate or poor surgical tec...
It is well documented that social housing is fundamental to good welfare for non-human primates (NHPs). Despite this, many laboratory NHPs around the world continue to be singly housed, thoug...
A problem facing the rapid growth of zebrafish as a model for human disease is a lack of qualified personnel that understand the benefits and limitations of fish culture. As this model gains...
I will present the most common hazards, as they are perceived by workers (traditionally zoonoses, bites and scratches, allergies).Then I will present real data on accidents in research faci...
The new animal facility is designed to breed and house rodents with the best quality of macro and micro environment and house the maximum possible number of rodents per sf2. This new facilit...
Understanding how genes coordinate their expression across cells in a growing embryo can provide insights into the transcriptional programs that control development. Intercellular variability...
The flexibility of the BioMark Real-Time PCR System, allow us to preform genetic research using different types of nano-fluidic (48.48 or 96.96) chips setup, in the thermal cycle of these chi...
The ENCODE and modENCODE consortia have generated a resource containing large amounts of transcriptomic data, extensive mapping of chromatin states, as well as the binding locations of >30...
As next-generation sequencing (NGS) platforms advance in their speed, ease-of-use, and cost-effectiveness, many translational researchers are transitioning from microarrays to RNA sequencing...
The human genome encodes ~21,500 proteins that are subject to reversible phosphorylation at nearly 1 million phosphosites by about 538 protein kinases and 156 protein phosphatases. Amongst ot...
Down syndrome (DS) is a complex multi-system disorder affecting more than 5.8 million individuals around the world and it causes significant physical, psychological, and cognitive abnormaliti...
Laboratory rats and mice are the most used animal species in scientific research, but still having a lot of information available about them, there are many places in Latin America where ther...
Informatics and internet are widely accepted tools in education and research. In the past decades new teaching and learning strategies have been developed and implemented. E-learning was def...
Intravascular catheterization access for injection and sampling is one of the most common experimental surgical procedures.Catheters and ports have been designed to reduce the problems of occ...
perioperative analgesia aims to minimize, or even eliminate pain during a surgical procedure. Currently this approach is rarely performed using a single analgesic drug and more commonly diff...
The zebrafish, Danio rerio, is an ideal model organism to address a broad array of biomedical questions, and is now widely employed to answer questions about aging, behavior, cancer, growth,...
All trainers are people but not all people are trainers. Several factors beyond the trainer influence the effectiveness of a safety training programs. This program will discuss the critical...
Oftentimes, by the time that laboratory animal facility personnel learn about a facility construction project, the project has been underway for quiet some time without their knowledge but mo...
We all have to provide training; if our program is big or small, a germ-free mouse colony or field studies in Africa, centralized or not. Animal research programs, as varied as they are, have...
The environment in which laboratory rodents are kept has an impact on experimental data and breeding performance. The quality of the environment is defined by both the quality of the primary...
The rise of zebrafish as a research model has been dramatic. Given the global nature of the work, the rise in shipping zebrafish as a laboratory species has been sharp. Up until this point th...
Biofilms, are defined as communities of microorganisms that grow embedded in a self-generated matrix of exopolysaccharides and adhered to an inert surface or a live tissue. They are formed 95...
The proper surgical techniques represent a key opportunity to improve the welfare of laboratory rodents, while meeting legal and ethical obligations. Use of inappropriate or poor surgical tec...
It is well documented that social housing is fundamental to good welfare for non-human primates (NHPs). Despite this, many laboratory NHPs around the world continue to be singly housed, thoug...
A problem facing the rapid growth of zebrafish as a model for human disease is a lack of qualified personnel that understand the benefits and limitations of fish culture. As this model gains...
I will present the most common hazards, as they are perceived by workers (traditionally zoonoses, bites and scratches, allergies).Then I will present real data on accidents in research faci...
The new animal facility is designed to breed and house rodents with the best quality of macro and micro environment and house the maximum possible number of rodents per sf2. This new facilit...