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Generics
A generic drug is developed with the same dosage form, safety, strength, route of administration, quality, performance characteristics, and intended use as a brand-name medication. Generics are known as bioequivalent to the name-brand drug, so they demonstrate the same degree of clinical benefit.
JUL 22, 2021 | 4:15 PM
Genome editing technologies have enabled the precise manipulation of DNA sequences at targeted sites to achieve therapeutic effects. Engineered endonucleases like CRISPR-Cas9 institute site-...
JUL 22, 2021 | 4:15 PM
Learning Objectives: 1. Background introduction to AAV gene therapy 2. Novel methods to build AAV capsid libraries for in vivo screening through rational design and directed evolution 3. Tis...
JUL 22, 2021 | 3:30 PM
Biocatalysis, protein engineering, and flow chemistry are key enabling technologies that can yield drastically shorter and greener chemical processes. We sought to leverage these technologie...
JUL 22, 2021 | 2:45 PM
AAV peptide display libraries allow for the generation of novel variants capable of high-level transduction. We previously described an AAV peptide display library combined with a sensitive...
JUL 22, 2021 | 2:45 PM
Learning Objectives: 1. CRISPR-Cas systems are naturally repurposes for non-canonical functions other than cleaving RNA and DNA 2. CRISPR RNA-guided transposases integrate donor DNA without...
JUL 22, 2021 | 1:30 PM
Genome Engineering allows the easy manipulation of genomes down to the nucleotide level. CRISPR is a revolutionizing tool for generating custom edited cell and pre-clinical animal models for...
JUL 22, 2021 | 12:45 PM
Though AsCas12a fills a crucial gap in the current genome editing toolbox, it exhibits relatively poor editing efficiency, restricting its overall utility. In collaboration with Integrated D...
