High throughput cell biology is the use of automation equipment with classical cell biology techniques to address biological questions that are otherwise unattainable using conventional methods. It may incorporate techniques from optics, chemistry, biology or image analysis to permit rapid, highly parallel research into how cells function, interact with each other and how pathogens exploit them in disease. High-throughput biology serves as one facet of what has also been called "omics research" - the interface between large scale biology (genome, proteome, transcriptome), technology and researchers. High throughput cell biology has a definite focus on the cell, and methods accessing the cell such as imaging, gene expression microarrays, or genome wide screening. The basic idea is to take methods normally performed on their own and do a very large number of them without impacting their quality.
As a computational scientist I have been fortunate to work with many collaborators to generate biological data to train and test my models. We are in a position with increasing amounts of dat...
DATE: September 15, 2015TIME: 10:00AM Pacific time, 1:00PM Eastern timeThe breadth of instruments available for quantitative PCR (qPCR) has continued to grow in the past 5-10 years. With ...
Cellular viability is usually determined by measuring the capacity of cells to exclude vital dyes such as 4',6-diamidino-2-phenylindole (DAPI), or by assessing nuclear morphology with chr...
Oxford Nanopore's MinION is a small, portable USB-powered sensing device which is powered by nanopore technology. It is adaptable to the analysis of DNA, RNA, proteins or small molecules, and...
Over the past twenty years there has been an accelerated attack on the use of preservatives in cosmetics. This increased scrutiny of preservatives has forced cosmetic companies to change thei...
Control of infection from methicillin resistant Staphylococcus aureus (MRSA) has been a healthcare focus for more than 50 years. One of the reasons that active surveillance testing (AST) for...
Respiratory viral infections remain a leading cause of medical visits and can contribute significantly to morbidity and mortality. Influenza, together with pneumonia, is the leading infectio...
Biofilm is an ancient and preferred mode of growth for microbes with 99% of all microbes residing in a biofilm. Biofilm is characterized by a community of microbes (usually polymicrobial ofte...
Polyamines are small, mostly linear organic molecules found in almost all living cells, and are positively charged at physiological pH. As a consequence of their positive charge, polyamines b...
DNASTAR offers an integrated suite of software for accurate assembly and analysis of sequence data for key NGS workflows, including microbial genome assembly. The DNASTAR assembly software is...
Advances in sequencing technology and increasing recognition of the importance of our microbial world have led to unprecedented discoveries in recent years with respect to the human microbiom...
The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
Managing microbial contaminants is critical during the manufacturing of biologics, food and beverage to ensure that products meet the high quality product standard as well as staying complian...
DATE: August 20, 2015TIME: 8:00am PDT, 11:00am EDT, 4:00pm BSTLight Sheet Microscopy for 3D live fluorescent imaging at high spatiotemporal resolution Dr Bi-Chang Chen will discuss his ...
Sign up here to watch this Webinar On DemandCytotoxicity remains one of the major causes of drug withdrawal and there is an urgent need for reliable and time-saving assay workflows. Cells exp...
Deep mutational scanning is a method that marries selection for protein function amongst a large library of protein variants with high-throughput DNA sequencing to measure the activity of hun...
I will present new insights into how multiomics profiling can be used to analyze and provide new insights into two complexes diseases, type 2 diabetes and autism....
I will discuss the use of genomic technologies - mostly ultrahigh-throughput DNA sequencing - to study normal human biology and to determine what goes wrong when we have disease. First I wil...
The continued growth of DNA sequencing as a fundamental data output has driven the need for the ability to generate high quality data from an increasing breadth of diminishing primary sample...
Technological advances in high throughput, low cost DNA sequencing coupled with the availability of a high quality reference assembly allow us to interrogate the genome with greater precision...
In recent years, sophisticated new methods for sedimentation data analysis have opened up new avenues for leveraging AUC technology in a wide range of technology sectors, including life scien...
Date: Tuesday, April 7th, 2015Time: 8:30AM PST, 11:30AM EST, 5:30PM CETThe development of new medicines for Diabetes Type 2 complications has proven to be challenging due to the use of cell...
In this presentation we will illustrate the advantages of AFA technology in clinically significant applications (NGS, FFPE, ChIP) and will demonstrate the flexibility of Covaris AFA in deliv...
As a computational scientist I have been fortunate to work with many collaborators to generate biological data to train and test my models. We are in a position with increasing amounts of dat...
DATE: September 15, 2015TIME: 10:00AM Pacific time, 1:00PM Eastern timeThe breadth of instruments available for quantitative PCR (qPCR) has continued to grow in the past 5-10 years. With ...
Cellular viability is usually determined by measuring the capacity of cells to exclude vital dyes such as 4',6-diamidino-2-phenylindole (DAPI), or by assessing nuclear morphology with chr...
Oxford Nanopore's MinION is a small, portable USB-powered sensing device which is powered by nanopore technology. It is adaptable to the analysis of DNA, RNA, proteins or small molecules, and...
Over the past twenty years there has been an accelerated attack on the use of preservatives in cosmetics. This increased scrutiny of preservatives has forced cosmetic companies to change thei...
Control of infection from methicillin resistant Staphylococcus aureus (MRSA) has been a healthcare focus for more than 50 years. One of the reasons that active surveillance testing (AST) for...
Respiratory viral infections remain a leading cause of medical visits and can contribute significantly to morbidity and mortality. Influenza, together with pneumonia, is the leading infectio...
Biofilm is an ancient and preferred mode of growth for microbes with 99% of all microbes residing in a biofilm. Biofilm is characterized by a community of microbes (usually polymicrobial ofte...
Polyamines are small, mostly linear organic molecules found in almost all living cells, and are positively charged at physiological pH. As a consequence of their positive charge, polyamines b...
DNASTAR offers an integrated suite of software for accurate assembly and analysis of sequence data for key NGS workflows, including microbial genome assembly. The DNASTAR assembly software is...
Advances in sequencing technology and increasing recognition of the importance of our microbial world have led to unprecedented discoveries in recent years with respect to the human microbiom...
The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
Managing microbial contaminants is critical during the manufacturing of biologics, food and beverage to ensure that products meet the high quality product standard as well as staying complian...
DATE: August 20, 2015TIME: 8:00am PDT, 11:00am EDT, 4:00pm BSTLight Sheet Microscopy for 3D live fluorescent imaging at high spatiotemporal resolution Dr Bi-Chang Chen will discuss his ...
Sign up here to watch this Webinar On DemandCytotoxicity remains one of the major causes of drug withdrawal and there is an urgent need for reliable and time-saving assay workflows. Cells exp...
Deep mutational scanning is a method that marries selection for protein function amongst a large library of protein variants with high-throughput DNA sequencing to measure the activity of hun...
I will present new insights into how multiomics profiling can be used to analyze and provide new insights into two complexes diseases, type 2 diabetes and autism....
I will discuss the use of genomic technologies - mostly ultrahigh-throughput DNA sequencing - to study normal human biology and to determine what goes wrong when we have disease. First I wil...
The continued growth of DNA sequencing as a fundamental data output has driven the need for the ability to generate high quality data from an increasing breadth of diminishing primary sample...
Technological advances in high throughput, low cost DNA sequencing coupled with the availability of a high quality reference assembly allow us to interrogate the genome with greater precision...
In recent years, sophisticated new methods for sedimentation data analysis have opened up new avenues for leveraging AUC technology in a wide range of technology sectors, including life scien...
Date: Tuesday, April 7th, 2015Time: 8:30AM PST, 11:30AM EST, 5:30PM CETThe development of new medicines for Diabetes Type 2 complications has proven to be challenging due to the use of cell...
In this presentation we will illustrate the advantages of AFA technology in clinically significant applications (NGS, FFPE, ChIP) and will demonstrate the flexibility of Covaris AFA in deliv...
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