Communication refers to the process by which a human (or non-human animal) transmits information, throughts, or ideas to another human/non-human animal. Oftentime, this communication has an impact on behavior as it causes the development of ideas, acts, or feelings upon receving the information.
Public, legal & ethical acceptability of animal research not only warrants respect for animal welfare & the 3Rs, but also that the perceived benefits can outweigh the pain, discomfort...
Animal models have provided an important tool to help make the decision to take potential therapies from preclinical studies to humans. In the past several years, the strong reliance of the p...
Surgerized animals play a crucial role in preclinical research aimed at drug and medical device discovery into treatments for humans. When implementing new in-house surgical models to perform...
Animal studies still play a crucial role in research aimed at improving human health care. When performing animal studies, the results and their interpretation are not always straightforward....
Translational failure in biomedicine has led to much soul-searching about the causes for this. Amongst many others (misunderstanding of statistical tests, vibration of effects, flexibility in...
Noise and vibration are very effective activators of stress pathways in rodent models that can increase variability in animal models, thereby confounding virtually every area of biomedical an...
Multidimensional molecular characterization has led to a tsunami of cancer data. Precision Medicine assumes that new understanding and better interventions will flow from this “Big Data...
The world–as microbes perceive it–is composed of physical and chemical stimuli. These stimuli create conditions that result in life or death for microbes, affecting their survival...
The NIH BRAIN initiative, informed by the report from the scientific community (BRAIN 2025) is underway. The major funded efforts at this time fit into 3 main categories; 1) defining the comp...
Recent advances in noninvasive neuroimaging have set the stage for the systematic exploration of human brain circuits in health and disease. The Human Connectome Project (HCP) is systematical...
As evidenced by the changes in the new Guide for the Care and Use of Laboratory animals and the latest AVMA Panel on Euthanasia, it is clear that there is growing concern about the care and w...
An anesthesia system designed to accommodate the physiological characteristics of small animals, including rats and mice, has the potential to provide great practical value to the life scienc...
Laboratory animal surgical models are instrumental in biomedical research; therefore establishing healthy defined animal models is crucial to this research. Surgical procedures produce metab...
Many researchers are not aware of the critical importance of genetic background of mice, including the concept of inbred substrains, and how the genetic background of substrains can impact th...
The field of surgical research has been growing rapidly with the development of new surgical and disease models. An extremely important and often overlooked aspect of creating these models is...
Soiled-bedding sentinels are not always efficient in detecting pathogens in rodent colonies. In this context, PCR-based testing can be more sensitive and is being advocated as adjunct to trad...
The era of omics has ushered in the hope for personalized medicine. Proteomic and genomic strategies that allow unbiased identification of genes and proteins and their post-transcriptional a...
In this presentation I describe pathway based analyses of genotyping data to identify pathways related to the development of complex diseases, with a focus on lung cancer and selected autoimm...
Informatics and internet are widely accepted tools in education and research. In the past decades new teaching and learning strategies have been developed and implemented. E-learning was def...
perioperative analgesia aims to minimize, or even eliminate pain during a surgical procedure. Currently this approach is rarely performed using a single analgesic drug and more commonly diff...
Oftentimes, by the time that laboratory animal facility personnel learn about a facility construction project, the project has been underway for quiet some time without their knowledge but mo...
It is well documented that social housing is fundamental to good welfare for non-human primates (NHPs). Despite this, many laboratory NHPs around the world continue to be singly housed, thoug...
A problem facing the rapid growth of zebrafish as a model for human disease is a lack of qualified personnel that understand the benefits and limitations of fish culture. As this model gains...
The question of pain in fish has been subject to much debate and, since fish are a popular experimental model globally and commercially important in fisheries, recreational angling and aquac...
Public, legal & ethical acceptability of animal research not only warrants respect for animal welfare & the 3Rs, but also that the perceived benefits can outweigh the pain, discomfort...
Animal models have provided an important tool to help make the decision to take potential therapies from preclinical studies to humans. In the past several years, the strong reliance of the p...
Surgerized animals play a crucial role in preclinical research aimed at drug and medical device discovery into treatments for humans. When implementing new in-house surgical models to perform...
Animal studies still play a crucial role in research aimed at improving human health care. When performing animal studies, the results and their interpretation are not always straightforward....
Translational failure in biomedicine has led to much soul-searching about the causes for this. Amongst many others (misunderstanding of statistical tests, vibration of effects, flexibility in...
Noise and vibration are very effective activators of stress pathways in rodent models that can increase variability in animal models, thereby confounding virtually every area of biomedical an...
Multidimensional molecular characterization has led to a tsunami of cancer data. Precision Medicine assumes that new understanding and better interventions will flow from this “Big Data...
The world–as microbes perceive it–is composed of physical and chemical stimuli. These stimuli create conditions that result in life or death for microbes, affecting their survival...
The NIH BRAIN initiative, informed by the report from the scientific community (BRAIN 2025) is underway. The major funded efforts at this time fit into 3 main categories; 1) defining the comp...
Recent advances in noninvasive neuroimaging have set the stage for the systematic exploration of human brain circuits in health and disease. The Human Connectome Project (HCP) is systematical...
As evidenced by the changes in the new Guide for the Care and Use of Laboratory animals and the latest AVMA Panel on Euthanasia, it is clear that there is growing concern about the care and w...
An anesthesia system designed to accommodate the physiological characteristics of small animals, including rats and mice, has the potential to provide great practical value to the life scienc...
Laboratory animal surgical models are instrumental in biomedical research; therefore establishing healthy defined animal models is crucial to this research. Surgical procedures produce metab...
Many researchers are not aware of the critical importance of genetic background of mice, including the concept of inbred substrains, and how the genetic background of substrains can impact th...
The field of surgical research has been growing rapidly with the development of new surgical and disease models. An extremely important and often overlooked aspect of creating these models is...
Soiled-bedding sentinels are not always efficient in detecting pathogens in rodent colonies. In this context, PCR-based testing can be more sensitive and is being advocated as adjunct to trad...
The era of omics has ushered in the hope for personalized medicine. Proteomic and genomic strategies that allow unbiased identification of genes and proteins and their post-transcriptional a...
In this presentation I describe pathway based analyses of genotyping data to identify pathways related to the development of complex diseases, with a focus on lung cancer and selected autoimm...
Informatics and internet are widely accepted tools in education and research. In the past decades new teaching and learning strategies have been developed and implemented. E-learning was def...
perioperative analgesia aims to minimize, or even eliminate pain during a surgical procedure. Currently this approach is rarely performed using a single analgesic drug and more commonly diff...
Oftentimes, by the time that laboratory animal facility personnel learn about a facility construction project, the project has been underway for quiet some time without their knowledge but mo...
It is well documented that social housing is fundamental to good welfare for non-human primates (NHPs). Despite this, many laboratory NHPs around the world continue to be singly housed, thoug...
A problem facing the rapid growth of zebrafish as a model for human disease is a lack of qualified personnel that understand the benefits and limitations of fish culture. As this model gains...
The question of pain in fish has been subject to much debate and, since fish are a popular experimental model globally and commercially important in fisheries, recreational angling and aquac...
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