Immune System: is the body's defense against infectious organisms and other invaders. The immune system is made up of a network of cells, tissues, and organs that work together to protect the body.
DATE: March 26, 2020 TIME: 9:00am PST, 12:00pm EST Growing demand for precision therapy and the recent successes with CAR-T cells for cancer treatment...
Identifying the diversity of neuronal cell types of the nervous system is one of the main objectives of the BRAIN Initiative, with the vision that distinct neuronal identities will allow for...
Working memory (the ability to hold some information in mind for a few seconds, and to manipulate that information) and decision-making (committing to one out of multiple possible choices) a...
Neurodegenerative disease research can be considerably accelerated by using fibrillar or oligomeric constructs of prion-like proteins in in vitro or in vivo studies. These exist in a variety...
Episodic memories are essential for human cognition, but the underlying neural mechanisms remain poorly understood. We utilize the opportunity to record in-vivo from human single neurons sim...
Learning is often an emotional process. Emotional stimuli with different valences, such as threat and reward, can transform an otherwise neutral sensory input into one that can trigger disti...
Approximately 300,000 people in the United States have a spinal cord injury with many of these individuals experiencing permanent motor and sensory deficits. For individuals with cervical sp...
Brain machine interfaces (BMIs) aim to help patients with paralysis to use their recorded brain activity to control assistive devices. BMI research requires the collaboration of neuroscienti...
Mechanistic understanding of neural systems is daunting to achieve in large part due to the heterogeneity of the neuronal elements in both form and function and the complexity of the circuit...
The neural basis of simple rhythmic and reflexive behaviors such as swimming and gill withdrawal have been successfully studied in nudibranchs and other gastropod molluscs because the brains...
The public health burden of Treatment Resistant Depression (TRD) has prompted clinical trials of deep brain stimulation (DBS) that have, unfortunately, produced inconsistent outcomes. Potent...
The accumulation of neurotoxic amyloid beta peptides and/or neurofibrillary tangle formation are key pathological hallmarks of neurodegenerative diseases including but not limited to Alzheim...
The US Brain Research through Advancing Innovative Neurotechnologies is a research program focused on building fundamental knowledge of how brain circuits process information to enable human...
Although neuroscience has provided a great deal of information about how neurons work, the fundamental question of how neurons function together in a network to produce cognition has been di...
Autosomal dominant missense mutations that hyperactivate the LRRK2 protein kinase are a common cause of inherited Parkinson’s disease and therapeutic efficacy of LRRK2 inhibitors is be...
Brain function is remarkably reliable despite the imprecise performance of neurons, and the continuous perturbations caused by aging, disease or injury. How does the brain succeed in produci...
Miltenyi Biotec offers a variety of neuroscience and immunology workflows that cover all steps from sample preparation and cell isolation to cell culture and flow cytometry. Discover the bre...
We present here a framework to generate a realistic multiscale circuit model of the larval zebrafish brain – the multiscale virtual fish (MVF). The model will be based on algorithms in...
The locomotion of humans and other animals requires a seamless flow of information from sensory modalities all the way to the motor periphery. As such, locomotion is an excellent system for...
Whether you are performing killing assays, characterizing the tumor microenvironment, or investigating immunogenicity, primary cells are essential for the discovery of new therapeutics. Conc...
Digital spatial profiling (DSP) on the NanoString GeoMx platform enables high plex molecular profiling of clinical tissue samples. This new profiling strategy enables deep insights into the...
Recent advances in DNA sequencing and omics-based capabilities are revealing incredible therapeutic opportunities and quickly transforming drug discovery. Molecularly targeted drugs aim to e...
Centhaquine (previously used names, centhaquin and PMZ-2010; International Non-proprietary Name (INN) recently approved by WHO is centhaquine) is being developed by us as a first-in-class re...
DATE: March 26, 2020 TIME: 9:00am PST, 12:00pm EST Growing demand for precision therapy and the recent successes with CAR-T cells for cancer treatment...
Identifying the diversity of neuronal cell types of the nervous system is one of the main objectives of the BRAIN Initiative, with the vision that distinct neuronal identities will allow for...
Working memory (the ability to hold some information in mind for a few seconds, and to manipulate that information) and decision-making (committing to one out of multiple possible choices) a...
Neurodegenerative disease research can be considerably accelerated by using fibrillar or oligomeric constructs of prion-like proteins in in vitro or in vivo studies. These exist in a variety...
Episodic memories are essential for human cognition, but the underlying neural mechanisms remain poorly understood. We utilize the opportunity to record in-vivo from human single neurons sim...
Learning is often an emotional process. Emotional stimuli with different valences, such as threat and reward, can transform an otherwise neutral sensory input into one that can trigger disti...
Approximately 300,000 people in the United States have a spinal cord injury with many of these individuals experiencing permanent motor and sensory deficits. For individuals with cervical sp...
Brain machine interfaces (BMIs) aim to help patients with paralysis to use their recorded brain activity to control assistive devices. BMI research requires the collaboration of neuroscienti...
Mechanistic understanding of neural systems is daunting to achieve in large part due to the heterogeneity of the neuronal elements in both form and function and the complexity of the circuit...
The neural basis of simple rhythmic and reflexive behaviors such as swimming and gill withdrawal have been successfully studied in nudibranchs and other gastropod molluscs because the brains...
The public health burden of Treatment Resistant Depression (TRD) has prompted clinical trials of deep brain stimulation (DBS) that have, unfortunately, produced inconsistent outcomes. Potent...
The accumulation of neurotoxic amyloid beta peptides and/or neurofibrillary tangle formation are key pathological hallmarks of neurodegenerative diseases including but not limited to Alzheim...
The US Brain Research through Advancing Innovative Neurotechnologies is a research program focused on building fundamental knowledge of how brain circuits process information to enable human...
Although neuroscience has provided a great deal of information about how neurons work, the fundamental question of how neurons function together in a network to produce cognition has been di...
Autosomal dominant missense mutations that hyperactivate the LRRK2 protein kinase are a common cause of inherited Parkinson’s disease and therapeutic efficacy of LRRK2 inhibitors is be...
Brain function is remarkably reliable despite the imprecise performance of neurons, and the continuous perturbations caused by aging, disease or injury. How does the brain succeed in produci...
Miltenyi Biotec offers a variety of neuroscience and immunology workflows that cover all steps from sample preparation and cell isolation to cell culture and flow cytometry. Discover the bre...
We present here a framework to generate a realistic multiscale circuit model of the larval zebrafish brain – the multiscale virtual fish (MVF). The model will be based on algorithms in...
The locomotion of humans and other animals requires a seamless flow of information from sensory modalities all the way to the motor periphery. As such, locomotion is an excellent system for...
Whether you are performing killing assays, characterizing the tumor microenvironment, or investigating immunogenicity, primary cells are essential for the discovery of new therapeutics. Conc...
Digital spatial profiling (DSP) on the NanoString GeoMx platform enables high plex molecular profiling of clinical tissue samples. This new profiling strategy enables deep insights into the...
Recent advances in DNA sequencing and omics-based capabilities are revealing incredible therapeutic opportunities and quickly transforming drug discovery. Molecularly targeted drugs aim to e...
Centhaquine (previously used names, centhaquin and PMZ-2010; International Non-proprietary Name (INN) recently approved by WHO is centhaquine) is being developed by us as a first-in-class re...