IVD, or in-vitro diagnostics are tests done on sample like blood or tissue that were taken from the human body. They can be used to detect diseases or other conditions and to monitor a person's overall health to help cure, treat, or prevent diseases.
Copy-number alterations and chromosomal translocations are widespread in cancer and frequently causing oncogenic mutations that drive tumorigenesis and therapy resistance. Despite their preva...
Background: The vast majority of all genes are contained within the genomes of the prokaryotes, including the eubacteria and the archaea. These largely single-cellular domains of life thus...
DATE: August 15, 2019TIME: 9:00am PDT, 12:00pm EDT Radiation therapy is a critical tool for the treatment of brain tumors, however, exposure to high doses of ionizing radiation...
Tissues in the body are wonderfully organized, with specific arrangements of cells, extracellular matrix, secreted molecules, and fluid flow that synergize that create emergent functions. How...
In-vitro epithelial barrier models that are more representative of in-vivo tissues are urgently needed. Here we present extracellular matrix-supported intestinal tubules in a perfused microfl...
Isolated hepatocytes or their enzymes comprise the basis of most in vitro DMPK and toxicity assays used to predict human hepatic outcomes. Because hepato-specific functions are typically lost...
Studies in drug development and on hematological and solid Tumors with a Thymidine Kinase 1 immunoassayThere are many tumor biomarkers but, they mostly reflect tumor mass or past growth,...
Recent clinical successes in cancer genome-inspired personalized medicine have been a major breakthrough in drug discovery. However, 98% of the patients have an incomplete therapeutic respons...
Solid phase microextraction (SPME) is a versatile, non-exhaustive sample preparation tool that has been demonstrated to be well-suited for facile and effective analysis of a broad range of co...
Although targeted therapies often elicit profound initial patient responses, these effects are transient due to residual disease leading to acquired resistance. How tumors transition between...
In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
Lateral flow assays (LFAs) are rapid, sensitive, and easy-to-use immunoassays for detecting specific target proteins in vitro. Although the LFA format is extremely popular in point-of-care di...
DATE: April 17, 2018TIME: 8:00AM PST, 11:00AM ESTRecently, much research has focused on obtaining 3D brain organoids in an attempt to better recapitulate brain development and function...
After this webinar you will be able to;- Describe the key challenges of Heart Failure Discuss the differences between natriuretic peptides BNP and NT-proBNP for the diagnosis, stratif...
The path form biomarker discovery to conversion to a clinically useful companion diagnostic test presents many challenges. The talk will outline the regulatory requirements to developing a su...
DATE: December 12, 2017TIME: 10:00AM PTSince their discovery, dendritic cells (DCs) have demonstrated a central role in the development of effective immune responses. Their unique abili...
Despite vast investment for decades in cancer research and development, cancer is still among the leading causes of death worldwide and its toll is expected to rise by about 70% over the next...
There have been significant increases in emergency room visits across the US and delays in the ED leads to poor outcomes. There is an association between waiting times and short term mo...
The recent Zika virus outbreak highlights the need for low-cost diagnostics that can be rapidly developed for distribution and use in pandemic regions. In early 2016 we developed a pipe...
Laboratory tests come into existence through a variety of processes but regardless of the genesis all share a certain set of requirements. These include discovery, development, validation, re...
The aim of the learning healthcare system is to leverage data stored in the electronic health record (EHR) to gain insights into and improve healthcare delivery. Laboratory testing represents...
Core or central laboratory are facing several challenges. First, the management and operations of a successful modern laboratory is a real complex exercise, with multiple pre- and post-analyt...
Sanger sequencing and polymerase chain reaction (PCR) methods have been the standard molecular methods in clinical diagnostics for decades. Next-Generation Sequencing (NGS) technology r...
The Solana GAS Assay is a rapid in vitro diagnostic test for the qualitative detection of Group A β-hemolytic Streptococcus (Streptococcus pyogenes) nucleic acids isolated from throat sw...
Copy-number alterations and chromosomal translocations are widespread in cancer and frequently causing oncogenic mutations that drive tumorigenesis and therapy resistance. Despite their preva...
Background: The vast majority of all genes are contained within the genomes of the prokaryotes, including the eubacteria and the archaea. These largely single-cellular domains of life thus...
DATE: August 15, 2019TIME: 9:00am PDT, 12:00pm EDT Radiation therapy is a critical tool for the treatment of brain tumors, however, exposure to high doses of ionizing radiation...
Tissues in the body are wonderfully organized, with specific arrangements of cells, extracellular matrix, secreted molecules, and fluid flow that synergize that create emergent functions. How...
In-vitro epithelial barrier models that are more representative of in-vivo tissues are urgently needed. Here we present extracellular matrix-supported intestinal tubules in a perfused microfl...
Isolated hepatocytes or their enzymes comprise the basis of most in vitro DMPK and toxicity assays used to predict human hepatic outcomes. Because hepato-specific functions are typically lost...
Studies in drug development and on hematological and solid Tumors with a Thymidine Kinase 1 immunoassayThere are many tumor biomarkers but, they mostly reflect tumor mass or past growth,...
Recent clinical successes in cancer genome-inspired personalized medicine have been a major breakthrough in drug discovery. However, 98% of the patients have an incomplete therapeutic respons...
Solid phase microextraction (SPME) is a versatile, non-exhaustive sample preparation tool that has been demonstrated to be well-suited for facile and effective analysis of a broad range of co...
Although targeted therapies often elicit profound initial patient responses, these effects are transient due to residual disease leading to acquired resistance. How tumors transition between...
In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
Lateral flow assays (LFAs) are rapid, sensitive, and easy-to-use immunoassays for detecting specific target proteins in vitro. Although the LFA format is extremely popular in point-of-care di...
DATE: April 17, 2018TIME: 8:00AM PST, 11:00AM ESTRecently, much research has focused on obtaining 3D brain organoids in an attempt to better recapitulate brain development and function...
After this webinar you will be able to;- Describe the key challenges of Heart Failure Discuss the differences between natriuretic peptides BNP and NT-proBNP for the diagnosis, stratif...
The path form biomarker discovery to conversion to a clinically useful companion diagnostic test presents many challenges. The talk will outline the regulatory requirements to developing a su...
DATE: December 12, 2017TIME: 10:00AM PTSince their discovery, dendritic cells (DCs) have demonstrated a central role in the development of effective immune responses. Their unique abili...
Despite vast investment for decades in cancer research and development, cancer is still among the leading causes of death worldwide and its toll is expected to rise by about 70% over the next...
There have been significant increases in emergency room visits across the US and delays in the ED leads to poor outcomes. There is an association between waiting times and short term mo...
The recent Zika virus outbreak highlights the need for low-cost diagnostics that can be rapidly developed for distribution and use in pandemic regions. In early 2016 we developed a pipe...
Laboratory tests come into existence through a variety of processes but regardless of the genesis all share a certain set of requirements. These include discovery, development, validation, re...
The aim of the learning healthcare system is to leverage data stored in the electronic health record (EHR) to gain insights into and improve healthcare delivery. Laboratory testing represents...
Core or central laboratory are facing several challenges. First, the management and operations of a successful modern laboratory is a real complex exercise, with multiple pre- and post-analyt...
Sanger sequencing and polymerase chain reaction (PCR) methods have been the standard molecular methods in clinical diagnostics for decades. Next-Generation Sequencing (NGS) technology r...
The Solana GAS Assay is a rapid in vitro diagnostic test for the qualitative detection of Group A β-hemolytic Streptococcus (Streptococcus pyogenes) nucleic acids isolated from throat sw...
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