DATE: November 2, 2017TIME: 10:00am PDT, 1:00pm EDTA CRISPR Way of Making MiceThe bulk of genetic variation associated with human disease exists in the noncoding genome, much of whi...
DATE: November 1, 2017TIME: 9:00am PT, 12:00pm ETOver 1.6 million people are diagnosed with sepsis in the U.S. each year1 and sepsis is the #1 cost of hospitalization (ove...
DATE: October 26, 2017TIME: 10:00am PT, 1:00pm ETMass spectrometry has gained tremendous interests in clinical applications in the past decade to serve patients needs. W...
DATE: October 25, 2017TIME: 10:00am PDT, 1:00pm EDTTesting for antinuclear antibodies (ANAs) has been a routine part of the evaluation of patients with a suspected connective tissue dis...
DATE: October 25, 2017TIME: 08:00am PDT, 11:00am EDTAs we learn more about the implications of genetic variation in 21st century medicine, the utilization of genotyping as a molecular t...
DATE: October 19, 2017TIME: 7:00 AM PDT, 10:00 AM EDT, 4:00 PM CETThis is the second topic in the webinar series on ‘Sanger Sequencing & Fragment Analysis made easy’...
DATE: October 18, 2017TIME: 8:00 AM PST, 11:00 AM ESTOver the past decade, 25-OH vitamin D has become one of the most common assays requested by physicians.The increase in testing volum...
DATE: October 17, 2017TIME: 08:00am PDT, 11:00am EDTResearching and understanding the mechanisms of drug resistance are essential to determine therapies that are more effective on an in...
The promise of precision and personalized medicine is rooted in accurate, highly sensitive, and specific disease biomarkers. This is particularly true for cancer-a disease characterized by ma...
Acral lentiginous melanoma (ALM) is a rare sun-shielded melanoma subtype associated with worse survival than cutaneous melanoma (CM), a more common form of skin cancer linked to exposure to u...
In order to expand the treatment options of cancers driven by oncogenic RAS, new cell surface targets need to be identified and characterized. Here, we describe mass spectrometry based phenot...
The detection of CTCs has been used as useful biomarkers in prognosis and monitoring therapeutic response of patients with metastatic cancer. However, during the course of cancer therapy, CTC...
The role played by inflammatory hypoxia in biology and treatment of solid tumors will be reviewed. The opportunity to enhance all forms of current anti-tumor therapies through tumor re-...
Colorectal cancer (CRC) is the third most common cancer among Americans, and the second deadliest. Its pathogenesis results from an interplay between environmental factors that influence biol...
Pancreatic cancer is one of the “deadly” cancers, defined as those with a 5-year relative survival rate of less than 50%. Although ranking 12th in terms of incidence, it is...
Exosomes are nano-scale lipid membrane-enclosed extracellular vesicles that form in the cellular endosomal system but are released outside the cell. These virus-sized “fat balls”...
More and more decisions will center on the ability to molecularly characterize a disease. So the molecular diagnostic laboratory will have a pivotal role. What does that look like? Will we be...
The first small molecule inhibitor of the molecular chaperone Heat Shock Protein 90 (HSP90) was identified more than 20 years ago. Upon determination of the drug binding site and clarificatio...
There has been a great deal of renewed attention in immuno-oncology over the last decade. Therapies for cancer are being developed, approved, and administered that can either initiate,...
DATE: October 10, 2017TIME: 9:00AM PDTPatient-derived xenografts (PDX) are increasingly being used in biomedical research for therapeutic analysis in mice. Unlike traditional cell line...
DATE: October 4th, 2017TIME: 8:00AM PT, 11:00AM ET, 5:00PM (GMT+2)New HCV drugs are now approved which, when used in combination, yield very high rates of cure of HC...
Traditional high throughput screening (HTS) assays for neuronal targets employ non-human primary neuronal cells due to the scale necessary for HTS. Isolation of mouse primary neurons can be u...
DATE: November 2, 2017TIME: 10:00am PDT, 1:00pm EDTA CRISPR Way of Making MiceThe bulk of genetic variation associated with human disease exists in the noncoding genome, much of whi...
DATE: November 1, 2017TIME: 9:00am PT, 12:00pm ETOver 1.6 million people are diagnosed with sepsis in the U.S. each year1 and sepsis is the #1 cost of hospitalization (ove...
DATE: October 26, 2017TIME: 10:00am PT, 1:00pm ETMass spectrometry has gained tremendous interests in clinical applications in the past decade to serve patients needs. W...
DATE: October 25, 2017TIME: 10:00am PDT, 1:00pm EDTTesting for antinuclear antibodies (ANAs) has been a routine part of the evaluation of patients with a suspected connective tissue dis...
DATE: October 25, 2017TIME: 08:00am PDT, 11:00am EDTAs we learn more about the implications of genetic variation in 21st century medicine, the utilization of genotyping as a molecular t...
DATE: October 19, 2017TIME: 7:00 AM PDT, 10:00 AM EDT, 4:00 PM CETThis is the second topic in the webinar series on ‘Sanger Sequencing & Fragment Analysis made easy’...
DATE: October 18, 2017TIME: 8:00 AM PST, 11:00 AM ESTOver the past decade, 25-OH vitamin D has become one of the most common assays requested by physicians.The increase in testing volum...
DATE: October 17, 2017TIME: 08:00am PDT, 11:00am EDTResearching and understanding the mechanisms of drug resistance are essential to determine therapies that are more effective on an in...
The promise of precision and personalized medicine is rooted in accurate, highly sensitive, and specific disease biomarkers. This is particularly true for cancer-a disease characterized by ma...
Acral lentiginous melanoma (ALM) is a rare sun-shielded melanoma subtype associated with worse survival than cutaneous melanoma (CM), a more common form of skin cancer linked to exposure to u...
In order to expand the treatment options of cancers driven by oncogenic RAS, new cell surface targets need to be identified and characterized. Here, we describe mass spectrometry based phenot...
The detection of CTCs has been used as useful biomarkers in prognosis and monitoring therapeutic response of patients with metastatic cancer. However, during the course of cancer therapy, CTC...
The role played by inflammatory hypoxia in biology and treatment of solid tumors will be reviewed. The opportunity to enhance all forms of current anti-tumor therapies through tumor re-...
Colorectal cancer (CRC) is the third most common cancer among Americans, and the second deadliest. Its pathogenesis results from an interplay between environmental factors that influence biol...
Pancreatic cancer is one of the “deadly” cancers, defined as those with a 5-year relative survival rate of less than 50%. Although ranking 12th in terms of incidence, it is...
Exosomes are nano-scale lipid membrane-enclosed extracellular vesicles that form in the cellular endosomal system but are released outside the cell. These virus-sized “fat balls”...
More and more decisions will center on the ability to molecularly characterize a disease. So the molecular diagnostic laboratory will have a pivotal role. What does that look like? Will we be...
The first small molecule inhibitor of the molecular chaperone Heat Shock Protein 90 (HSP90) was identified more than 20 years ago. Upon determination of the drug binding site and clarificatio...
There has been a great deal of renewed attention in immuno-oncology over the last decade. Therapies for cancer are being developed, approved, and administered that can either initiate,...
DATE: October 10, 2017TIME: 9:00AM PDTPatient-derived xenografts (PDX) are increasingly being used in biomedical research for therapeutic analysis in mice. Unlike traditional cell line...
DATE: October 4th, 2017TIME: 8:00AM PT, 11:00AM ET, 5:00PM (GMT+2)New HCV drugs are now approved which, when used in combination, yield very high rates of cure of HC...
Traditional high throughput screening (HTS) assays for neuronal targets employ non-human primary neuronal cells due to the scale necessary for HTS. Isolation of mouse primary neurons can be u...