Molecular Diagnostics: Molecular diagnostic tests detect specific sequences in DNA or RNA that may or may not be associated with disease, including single nucleotide polymorphism (SNP), deletions, rearrangements, insertions and others. By analysing the specifics of the patient and their disease, molecular diagnostics offers the prospect of personalized medicine. These tests are useful in a range of medical specialisms, including infectious disease, oncology, human leucocyte antigen typing, coagulation, and pharmacogenomics-the genetic prediction of which drugs will work best.
Impulse control disorders (ICDs), also known as behavioural addictions, are common in the general population and can have marked consequences. ICDs can also commonly occur with exposure...
This talk will provide an overview of Fourier Transform InfraRed (FTIR) chemical imaging as a powerful and versatile method for obtaining information about CNS tissues. By combining imaging a...
Traditional models of basal ganglia disorders are grounded in the assumption that network dysfunction is driven by alterations in intrinsic excitability of striatal neurons. Recent work has c...
Innovation in Psychopharmacology is Dead. Long Live Innovation in Psychopharmacology! What’s going on in our field? Priorities of Big Pharma shifting away fr...
In the adult central nervous system (CNS) small populations of neurons are formed in the adult olfactory bulb and dentate gyrus of the hippocampus. In the adult hippocampus, newly born neuron...
We routinely face decisions requiring evaluation and choice of different actions may or may not yield different types of rewards. These situations trigger competitive decision biases that ref...
Optogenetics or optophysiology is a rapidly growing technique used across an ever broadening array of research fields. Investigators now genetically modify many signalling pathway elements to...
Our goal - To Understand the Neurobiology of Emotions and Affect and Its Relevance to Psychiatric Disorders. This includes: Understanding basic mechanisms of affect, stre...
Understanding disease at a deeper level so that it can be targeted more precisely is the essence of precision medicine. Rapid technological advance, particularly in genomics and sensor-based...
A number of recently publications have heralded the advent of Precision Medicine in Oncology, where next generation sequencing technology, other ’omics technologies, serial biopsies, so...
In December 2012 the UK Prime Minister announced the 100,000 genomes project to introduce whole genome sequencing for treatment into the UK National Health Service (NHS) o...
The reproducibility of animal studies is now critical to ensure that limited resources are used wisely and that efforts yield useable knowledge. At this time, IACUCs and other similar a...
This presentation will discuss variables in rodent colony management that can affect colony breeding efficiency, rodent health, and factors that can modulate rodent models of disease. V...
Reproducibility refers to the ability of an experiment or study to be replicated, either by the same person or group or by others working independently. With regard to scientific public...
January 12, 2016, 8:00am PT, 11:00am ET, 3:00pm GMT
Targeted nanoparticle applications have become a major focus of translational development of both diagnostics and therapeutics for clini...
Date: December 9, 2015 10AM Pacific, 1PM Eastern
July 7, 2015, the U.S. Food and Drug Administration reviewed and approved ENTRESTO™ (sacubitril/valsartan) tablets to reduce the risk...
While genomics has been used as a tool for research for many years, globally there is increasing momentum to deploy microbial genomics for routine public health microbiology. This technology...
The assessment of serum lipid and lipoprotein levels is a common procedure which affects the management of the risk of atherothrombotic cardiovascular disease (CVD) in large numbers of patien...
Currently, next-generation sequencing is not only being used for basic discovery research but also in clinical settings for translational biomarker profiling and clinical research studies inc...
Diagnostic error impacts millions of US adults and children every year1,2. Failure to order an appropriate diagnostic test and incorrect interpretation of diagnostic test results are co...
Basic research in Proteomics has led to new understanding of proteins’ contributions to health and disease, and has also driven the advancement of powerful analytical technologies used...
Hyperthyroidism is an autoimmune disorder caused by the thyroid stimulating antibody (TSI), active against the thyroid-stimulating hormone (TSH) receptor, which stimulates the gland to synthe...
Appropriate dosing of pharmaceuticals is critical to prevent sub-therapeutic efficacy or the occurrence of adverse events. However, genetic variability may significantly influence an individu...
Introduction and adoption of whole-genome sequencing has enabled new methods of investigation in the quest for answers in diagnostic odyssey cases as well as in the broader study of genetic d...
Impulse control disorders (ICDs), also known as behavioural addictions, are common in the general population and can have marked consequences. ICDs can also commonly occur with exposure...
This talk will provide an overview of Fourier Transform InfraRed (FTIR) chemical imaging as a powerful and versatile method for obtaining information about CNS tissues. By combining imaging a...
Traditional models of basal ganglia disorders are grounded in the assumption that network dysfunction is driven by alterations in intrinsic excitability of striatal neurons. Recent work has c...
Innovation in Psychopharmacology is Dead. Long Live Innovation in Psychopharmacology! What’s going on in our field? Priorities of Big Pharma shifting away fr...
In the adult central nervous system (CNS) small populations of neurons are formed in the adult olfactory bulb and dentate gyrus of the hippocampus. In the adult hippocampus, newly born neuron...
We routinely face decisions requiring evaluation and choice of different actions may or may not yield different types of rewards. These situations trigger competitive decision biases that ref...
Optogenetics or optophysiology is a rapidly growing technique used across an ever broadening array of research fields. Investigators now genetically modify many signalling pathway elements to...
Our goal - To Understand the Neurobiology of Emotions and Affect and Its Relevance to Psychiatric Disorders. This includes: Understanding basic mechanisms of affect, stre...
Understanding disease at a deeper level so that it can be targeted more precisely is the essence of precision medicine. Rapid technological advance, particularly in genomics and sensor-based...
A number of recently publications have heralded the advent of Precision Medicine in Oncology, where next generation sequencing technology, other ’omics technologies, serial biopsies, so...
In December 2012 the UK Prime Minister announced the 100,000 genomes project to introduce whole genome sequencing for treatment into the UK National Health Service (NHS) o...
The reproducibility of animal studies is now critical to ensure that limited resources are used wisely and that efforts yield useable knowledge. At this time, IACUCs and other similar a...
This presentation will discuss variables in rodent colony management that can affect colony breeding efficiency, rodent health, and factors that can modulate rodent models of disease. V...
Reproducibility refers to the ability of an experiment or study to be replicated, either by the same person or group or by others working independently. With regard to scientific public...
January 12, 2016, 8:00am PT, 11:00am ET, 3:00pm GMT
Targeted nanoparticle applications have become a major focus of translational development of both diagnostics and therapeutics for clini...
Date: December 9, 2015 10AM Pacific, 1PM Eastern
July 7, 2015, the U.S. Food and Drug Administration reviewed and approved ENTRESTO™ (sacubitril/valsartan) tablets to reduce the risk...
While genomics has been used as a tool for research for many years, globally there is increasing momentum to deploy microbial genomics for routine public health microbiology. This technology...
The assessment of serum lipid and lipoprotein levels is a common procedure which affects the management of the risk of atherothrombotic cardiovascular disease (CVD) in large numbers of patien...
Currently, next-generation sequencing is not only being used for basic discovery research but also in clinical settings for translational biomarker profiling and clinical research studies inc...
Diagnostic error impacts millions of US adults and children every year1,2. Failure to order an appropriate diagnostic test and incorrect interpretation of diagnostic test results are co...
Basic research in Proteomics has led to new understanding of proteins’ contributions to health and disease, and has also driven the advancement of powerful analytical technologies used...
Hyperthyroidism is an autoimmune disorder caused by the thyroid stimulating antibody (TSI), active against the thyroid-stimulating hormone (TSH) receptor, which stimulates the gland to synthe...
Appropriate dosing of pharmaceuticals is critical to prevent sub-therapeutic efficacy or the occurrence of adverse events. However, genetic variability may significantly influence an individu...
Introduction and adoption of whole-genome sequencing has enabled new methods of investigation in the quest for answers in diagnostic odyssey cases as well as in the broader study of genetic d...
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