Molecular research and diagnostics are processes that take analyze DNA to identify markers or alterations that confer a disease or disorder. Testing can be performed to diagnose infectious diseases such as influenza, tuberculosis, or SARS-CoV-2.
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Axonal growth and pathfinding is fundamental to the development and regeneration of the nervous system. Src tyrosine kinase has been implicated in this process; however, the detailed molecula...
Synaptic dysfunction and loss caused by age-dependent accumulation of synaptotoxic Amyloid beta (Abeta)1-42 oligomers is proposed to underlie cognitive decline in Alzheimers disease (AD). Syn...
Neuron-glial interactions are increasingly recognized as being key for physiological and pathological processes in the central nervous system. Microglia have been found to play a causal role...
We present a personalized medicine suite of software applications developed at UCSF for multiple sclerosis (MS): the MS Bioscreen. This new tool addresses the challenges of the dynamic manage...
Discrimination against women has typically been attributed to hostile and demeaning stereotypes about womens capabilities. However, a growing body of evidence shows that subjectively positive...
When speaking of neurodegenerative diseases, average public is not made aware of the true cost that brain related disorders have on annual budget. The true impact on economy is not usually...
Dendritic spine shape enables sequestering of subcellular components needed for synaptic plasticity, including polyribosomes for local protein synthesis, smooth endoplasmic reticulum (SER) to...
Multiple Sclerosis is a debilitating neurodegnerative disease of the central nervous system in which the immune system targets and destroys myelin sheaths surrounding axons. Progressive a...
The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is part of a new Presidential focus aimed at revolutionizing our understanding of the human brain. By...
Multiple Sclerosis (MS) is an autoimmune disease that leads to widespread pathology within the central nervous system (CNS) and is the most common cause of neurologic disability among young a...
Down syndrome (DS) is a complex multi-system disorder affecting more than 5.8 million individuals around the world and it causes significant physical, psychological, and cognitive abnormaliti...
In physical systems built with many components, emergent properties, such as magnetism, are often generated from the interactions among these particles. These emergent properties are often in...
Making precision cancer care a future reality requires novel approachesto finding treatment targets in cancers. Single-gene assays currently performed in clinical research laboratories are in...
FEB 06, 2014 | 12:00 PM
C.E. CREDITS
The zebrafish, Danio rerio, is an ideal model organism to address a broad array of biomedical questions, and is now widely employed to answer questions about aging, behavior, cancer, growth,...
The rise of zebrafish as a research model has been dramatic. Given the global nature of the work, the rise in shipping zebrafish as a laboratory species has been sharp. Up until this point th...
The 2011 Guide for the Care and Use of Laboratory Animals has required that institutions place importance on assuring that staff working with animals are trained and competent to perform thei...
FEB 05, 2014 | 2:00 PM
C.E. CREDITS
It is increasingly recognized that the genetic background (i.e., all genomic sequences other than the gene(s) of interest) can have profound influences on the phenotype of an animal model. I...
Training for researchers using animals is a requirement in most European countries. However, somewhat surprisingly, the main actor in providing specific guidelines for such training is a scie...