Understanding mouse behavior is vital for researchers using murine models for scientific analysis. Mice are nocturnal animals, usually preferring to sleep during the day and eat and perform activity at night. Mice are a social species and thus are typically caged in groups or 4 - 5 mice. Male mice behave territorially and thus will not tolerate other males in their cages so male laboratory mice should not be mixed post-weaning. Females tend to be less aggressive than males.
-
FEB 05, 2015 | 6:00 AM
C.E. CREDITS
Many researchers are not aware of the critical importance of genetic background of mice, including the concept of inbred substrains, and how the genetic background of substrains can impact th...
Down syndrome (DS) is a complex multi-system disorder affecting more than 5.8 million individuals around the world and it causes significant physical, psychological, and cognitive abnormaliti...
We all have to provide training; if our program is big or small, a germ-free mouse colony or field studies in Africa, centralized or not. Animal research programs, as varied as they are, have...
The utility of dried blood spot (DBS) sampling technology for rodent colony health monitoring was investigated using a two-tiered approach. In the first approach, groups of mice and rats were...
The popularity reached by the genetic manipulation of laboratory animals to create new models for studying human diseases, produced in turn, that the techniques for assisted reproduction cons...
FEB 05, 2014 | 2:00 PM
C.E. CREDITS
It is increasingly recognized that the genetic background (i.e., all genomic sequences other than the gene(s) of interest) can have profound influences on the phenotype of an animal model. I...
With the growth and expansion of mouse and rat transgenic models in recent years, the demand for surgically altered models mimicking human diseases is growing at an amazing rate. Surgical pro...