Pharmacology: the branch of biology concerned with the study of drug action, where a drug can be broadly defined as any man-made, natural, or endogenous molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals.
Learning Objectives: 1. Describe the exposure response relationships with vancomycin and acute kidney injury 2. Define biomarkers that may be useful to improve Precision Dosing...
Microphysiological systems (MPS), also known as organ-on-chips, are small scale in vitro cell cultures which mimic facets of tissue or organ level function. MPS frequently utilise primary hu...
The dopamine D4 receptor (D4R) is enriched in the prefrontal cortex where it plays important roles in cognition, attention, decision making and executive function. Novel D4R-selective ligand...
Open Science has changed research by making data accessible and shareable, contributing to replicability to accelerate and disseminate knowledge. However, for rodent cognitive studies the av...
DATE: December 17, 2019 TIME: 2:00pm SGT From WHO 2017 Hepatitis report, an estimated 290 million (89%) of the 325 million people living with viral hepatitis B and C are unaware that they ar...
DATE: December 4, 2019 TIME: 9:00am PST, 12:00pm EST Targeted protein degradation is a novel chemical modality centered on using pharmacological agents to immediately and select...
DATE: December 4, 2019TIME: 7:00am PST, 10:00am EST, 4:00pm CET Do you know how it feels when you just quickly want to redo an experiment that your colleague did, or an experim...
DATE: November 18, 2019TIME: 7:00am PST, 11:00am EST, 4:00pm CEWT How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop th...
The Laboratory Stewardship Committee of the Cleveland Clinic is a multidisciplinary team of clinicians, pathologists, administrators, nurses and other caregivers. The team has a commitment t...
Part 1: Sustainable health and laboratory medicine; Presented by Professor Damien GrusonSummary: PendingPart 2: Let’s talk about errors in point of care testing in mobile health...
Thyroid autoimmunity (TAI) tends to be more common in women consulting for fertility problems. However, any underlying causal mechanism connecting TAI to fertility aspects is yet to be establ...
Thyroid function tests play a central role to assess thyroid function and are valuable companions for clinicians. The evolution of the tests is permanent and clinical laboratories are key pla...
Breast cancer is the most frequently occurring form of cancer in women. While 5-year survival rates for localized disease approach 99%, cases of advanced breast cancer have a much poorer pro...
Random drug testing is used as a preventive and detection tool for drug or alcohol use, and medication compliance in the monitoring of regulatory and treatment compliance monitoring. Urine sc...
Central to the diagnosis and management of patients with diabetes mellitus is the measurement of hemoglobin A1c (HbA1c). Major studies have defined the therapeutic targets of HbA1c in order...
Applying machine learning methods to structured, expert-curated content from scientific literature is a powerful way to discover latent knowledge. Building on the QIAGEN Knowledge Base, we us...
70,237 drug overdose deaths occurred in the United States in 2017 and opioids were involved in 47,600 of those deaths (67.8%).1 Ohio had the second highest rate of opioid overdose deaths in t...
Facioscapulohumeral muscular dystrophy (FSHD), one of the most common forms of progressive muscular dystrophies and is often conventionally diagnosed by Southern blot analysis. The accurate d...
Burn patients are at risk for organ dysfunction secondary to “burn shock” and sepsis. The initial 24 hours following major burn injury presents with significant hypotension due to...
The efficacy of current influenza antiviral drugs is compromised by emerging drug resistance. To address this unmet medical need, we have made progress in developing novel influenza antiviral...
DATE: October 2, 2019TIME: 9:00am PTThe Clampfit software module is a useful tool to manipulate and analyze electrophysiological data acquired by pCLAMP™ software. Recently, Mol...
The active shaping of biological membranes is essential for a variety of cellular functions including but not limited to cell migration, cell division, organelle morphology, and cell and memb...
Learning Objectives: Review basic immuno-pathobiology of IBD and the phenotypes of IBD or IBDs - Crohn’s, Ulcerative Colitis and Indeterminate Colitis Briefly describe the epide...
DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
Learning Objectives: 1. Describe the exposure response relationships with vancomycin and acute kidney injury 2. Define biomarkers that may be useful to improve Precision Dosing...
Microphysiological systems (MPS), also known as organ-on-chips, are small scale in vitro cell cultures which mimic facets of tissue or organ level function. MPS frequently utilise primary hu...
The dopamine D4 receptor (D4R) is enriched in the prefrontal cortex where it plays important roles in cognition, attention, decision making and executive function. Novel D4R-selective ligand...
Open Science has changed research by making data accessible and shareable, contributing to replicability to accelerate and disseminate knowledge. However, for rodent cognitive studies the av...
DATE: December 17, 2019 TIME: 2:00pm SGT From WHO 2017 Hepatitis report, an estimated 290 million (89%) of the 325 million people living with viral hepatitis B and C are unaware that they ar...
DATE: December 4, 2019 TIME: 9:00am PST, 12:00pm EST Targeted protein degradation is a novel chemical modality centered on using pharmacological agents to immediately and select...
DATE: December 4, 2019TIME: 7:00am PST, 10:00am EST, 4:00pm CET Do you know how it feels when you just quickly want to redo an experiment that your colleague did, or an experim...
DATE: November 18, 2019TIME: 7:00am PST, 11:00am EST, 4:00pm CEWT How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop th...
The Laboratory Stewardship Committee of the Cleveland Clinic is a multidisciplinary team of clinicians, pathologists, administrators, nurses and other caregivers. The team has a commitment t...
Part 1: Sustainable health and laboratory medicine; Presented by Professor Damien GrusonSummary: PendingPart 2: Let’s talk about errors in point of care testing in mobile health...
Thyroid autoimmunity (TAI) tends to be more common in women consulting for fertility problems. However, any underlying causal mechanism connecting TAI to fertility aspects is yet to be establ...
Thyroid function tests play a central role to assess thyroid function and are valuable companions for clinicians. The evolution of the tests is permanent and clinical laboratories are key pla...
Breast cancer is the most frequently occurring form of cancer in women. While 5-year survival rates for localized disease approach 99%, cases of advanced breast cancer have a much poorer pro...
Random drug testing is used as a preventive and detection tool for drug or alcohol use, and medication compliance in the monitoring of regulatory and treatment compliance monitoring. Urine sc...
Central to the diagnosis and management of patients with diabetes mellitus is the measurement of hemoglobin A1c (HbA1c). Major studies have defined the therapeutic targets of HbA1c in order...
Applying machine learning methods to structured, expert-curated content from scientific literature is a powerful way to discover latent knowledge. Building on the QIAGEN Knowledge Base, we us...
70,237 drug overdose deaths occurred in the United States in 2017 and opioids were involved in 47,600 of those deaths (67.8%).1 Ohio had the second highest rate of opioid overdose deaths in t...
Facioscapulohumeral muscular dystrophy (FSHD), one of the most common forms of progressive muscular dystrophies and is often conventionally diagnosed by Southern blot analysis. The accurate d...
Burn patients are at risk for organ dysfunction secondary to “burn shock” and sepsis. The initial 24 hours following major burn injury presents with significant hypotension due to...
The efficacy of current influenza antiviral drugs is compromised by emerging drug resistance. To address this unmet medical need, we have made progress in developing novel influenza antiviral...
DATE: October 2, 2019TIME: 9:00am PTThe Clampfit software module is a useful tool to manipulate and analyze electrophysiological data acquired by pCLAMP™ software. Recently, Mol...
The active shaping of biological membranes is essential for a variety of cellular functions including but not limited to cell migration, cell division, organelle morphology, and cell and memb...
Learning Objectives: Review basic immuno-pathobiology of IBD and the phenotypes of IBD or IBDs - Crohn’s, Ulcerative Colitis and Indeterminate Colitis Briefly describe the epide...
DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
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