Follow
Pluripotency
Pluripotency: illustrates the ability of a cell to develop into the three primary germ cell layers of the early embryo and therefore into all cells of the adult body, but not extra-embryonic tissues such as the placenta. Embryonic stem cells and induced pluripotent stem cells are defined by their pluripotency.
APR 17, 2018 | 8:00 AM
DATE: April 17, 2018TIME: 8:00AM PST, 11:00AM ESTRecently, much research has focused on obtaining 3D brain organoids in an attempt to better recapitulate brain development and function...
MAR 28, 2018 | 10:00 AM
DATE: March 28, 2018TIME: 10:00am PDT, 01:00pm EDTPrimary cells are derived from various tissues typically via dissection, enzymatic dissociation, and subsequent culture in media specif...
MAR 14, 2018 | 9:00 AM
Biomedical research depends on the use of model systems to explore basic biology, probe disease mechanisms, and conduct drug discovery and development. However, results from such systems are...
MAR 01, 2018 | 12:00 AM
The isolation of human embryonic stem cells (hESCs) and the discovery of human induced pluripotent stem cell (hiPSC) reprogramming have sparked a renaissance in stem cell biology, in vitro di...
FEB 01, 2018 | 12:00 AM
Pluripotent stem cells can reproduce indefinitely and develop into any cell type in the body. We are putting pluripotent stem cells to use, for a neuron replacement therapy for Parkinso...
JAN 01, 2018 | 10:00 AM
The capacity to generate disease-relevant cell populations from human pluripotent stem cells has tremendous potential for shedding light on human disease mechanisms. I will discuss basic prin...
JAN 01, 2018 | 12:00 AM
My talk shall encompass how the stem cell research field has evolved from embryonic stem cells to adult stem cells and currently induced pluripotent stem cells with special reference to the f...
DEC 01, 2017 | 12:00 AM
The use of pluripotent stem cells is dramatically altering the R&D landscape, providing new insights into both the basic biology of disease progression and novel cell types for pharmaceut...
NOV 09, 2017 | 10:00 AM
Therapeutic development for human diseases continues to face obstacles, particularly in translating targets or compounds identified by in vitro screening campaigns to valid targets or efficac...
NOV 09, 2017 | 4:00 AM
Derivation of many different cell types from human pluripotent stem cells (embryonic stem cells or HESCs and induced pluripotent stem cells or hiPS cells) is an area of growing interest both ...
NOV 08, 2017 | 6:00 PM
Regulatory non coding RNAs, including microRNAs (miRNAs) and long non coding RNAs (lncRNAs), have shown to be essential for animal development and viability, yet dissecting the relevance of i...
NOV 01, 2017 | 12:00 AM
For more than four decades, restrictions on research with psychoactive drugs have slowed progress in understanding how such substances impact brain metabolism. Besides the historical restrict...
OCT 12, 2017 | 1:30 PM
The deposition and removal of DNA and histone modifications depends on the availability of specific metabolites, suggesting that cellular metabolic pathways may dynamically regulate chromatin...
OCT 12, 2017 | 6:00 AM
We developed two computational methods, CARE and TIDE, to predict response and resistance to targeted therapies and immunotherapies. CARE infers gene signatures of targeted therapy response b...
OCT 01, 2017 | 12:00 AM
Traditional high throughput screening (HTS) assays for neuronal targets employ non-human primary neuronal cells due to the scale necessary for HTS. Isolation of mouse primary neurons can be u...
SEP 28, 2017 | 10:30 AM
Stem cells can self-renew and differentiate into multiple different cell types. Engineering of stem cells has enabled new methods to study development and organogenesis in humans as well as d...
