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Therapeutic protein characterization
Therapeutic proteins are specially designed for a particular clinical approach. Therapeutic proteins must be extensively characterized to detect molecular variants which can develop naturally or during the manufacturing or storage processes. Any modifications to the protein can impact the therapeutic efficacy and thus they must be closely monitored during development and administration.
OCT 07, 2021 | 8:00 AM
Date: October 7, 2021 Time: 8:00am (PDT), 11:00am (EDT) To combat the COVID-19 pandemic, comprehensive characterization of humoral and cellular immune responses to SARS-CoV-2 is essential. A...
OCT 05, 2021 | 7:00 AM
Date: October 05, 2021 Time: 7:00am (PDT), 10:00am (EDT) After new users become familiar with flow cytometry instrumentation and learn how to set up the instrument and acquire data, the next...
SEP 22, 2021 | 11:59 PM
Microtubule plus-end tracking proteins (+TIPs) play key roles in the regulation of microtubule dynamics in vivo. These proteins bind to and regulate microtubule “plus‐ends”, whic...
AUG 25, 2021 | 7:30 AM
The misfolding of intrinsically disordered proteins (IDPs) such as tau and α-synuclein (αSyn) has been associated with the on-set and progression of Alzheimer’s (AD) and Pa...
AUG 25, 2021 | 12:00 AM
Ataxia Telangiectasia, also known as A-T, is a devastating neuropediatric and genetic disorder for which there is no cure. Patients suffer from immune deficiency, cancer predisposition, and...
AUG 25, 2021 | 12:00 AM
Parkinson’s disease (PD) is the second most common neurodegenerative disorder with multiple motor and non-motor symptoms. PD is characterized by the presence on proteinaceous neuronal...
AUG 24, 2021 | 11:00 AM
Date: August 24, 2021 Time: 11:00am (PDT), 1:00pm (EDT) Electron-based dissociation mechanisms have shown great promise for advanced characterization of biomolecules. However, routine adopti...
JUN 02, 2021 | 3:00 PM
PD-L1 is a key inhibitor of T cell activation that is often over-expressed in cancer to escape immune surveillance and promote tumor progression. Blocking antibodies against PD-L1 or its rec...
MAY 13, 2021 | 8:00 AM
Date: May 13, 2021 Time: 8:00am (PDT), 11:00am (EDT) Antibodies are the most rapidly growing form of therapeutic. High-throughput methods of characterization are essential as companies and r...
APR 01, 2021 | 8:00 AM
Date: April 01, 2021 Time: 8:00am (PST), 11:00am (EST) Generating therapeutic antibodies is far more challenging than obtaining antibodies that merely recognize their targets. Engineering po...
MAR 18, 2021 | 9:00 AM
Date: March 18, 2021 Time: 9:00am (PST), 12:00am (EST) As novel therapeutic modalities progress through development, improved analytical techniques are required to overcome characterization...
FEB 10, 2021 | 8:00 AM
Date: February 10, 2021 Time: 8:00am (PST), 11:00am (EST) Uncovering the interactions between the immune system and cancer cells or pathogens is key for understanding and controlling both ca...
DEC 10, 2020 | 8:00 AM
Date: December 10, 2020 Time: 8:00am (PST), 11:00am (EST) As you face increasingly shortened timelines to bring new drugs to market, you find yourself strained to finalize analytical methods...
DEC 09, 2020 | 7:00 AM
Date: December 9, 2020 Time: 7:00am (PST), 10:00am (EST) In this talk we will discuss the new analytical approaches to characterize RNA molecules from small oligonucleotides to larger messen...
DEC 03, 2020 | 4:30 PM
This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
NOV 20, 2020 | 8:00 AM
DATE: November 20, 2020 TIME: 8am PDT, 11am EDT Insulin-like growth factor-1 (IGF-1) measurement by high-resolution accurate mass-mass spectrometry (HRAM) is replacing IGF-1 immunoassays and...
NOV 19, 2020 | 9:00 AM
DATE: November 19, 2020 TIME: 9:00am PT, 12am ET Knowledge of the three-dimensional structure of therapeutically relevant targets has become an essential step in the pipeline of drug discove...
NOV 19, 2020 | 8:00 AM
Date: November 19, 2020 Time: 8:00am PST, 11:00am EST Monoclonal antibody-based drugs have shown great potential as a treatment for several cancers. At Miltenyi Biotec, we offer a complete wo...
NOV 12, 2020 | 10:00 AM
Date: November 12, 2020 Time: 10:00am (PST), 1:00pm (EST) Fc receptor based affinity chromatography is a new emerging field of Fc functionality analytics. FcRn affinity columns separate anti...
NOV 12, 2020 | 12:00 AM
Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
