Therapeutic proteins are specially designed for a particular clinical approach. Therapeutic proteins must be extensively characterized to detect molecular variants which can develop naturally or during the manufacturing or storage processes. Any modifications to the protein can impact the therapeutic efficacy and thus they must be closely monitored during development and administration.
CALIXAR has developed an innovative detergent/surfactant based approach consisting on native isolation and stabilization of therapeutic membrane protein targets such as GPCRs, ion channels, t...
G protein coupled receptors (GPCRs) are the targets of 30-40% of all approved drugs. However many approaches successfully applied to drug discovery for soluble protein targets have made a lim...
Parkinson’s disease (PD) is characterized by the loss of dopamine and the disruption of brain circuits (basal ganglia and cortex) that are responsible for normal cognitive and motor per...
Our decisions are governed by a balance between prospective instrumental goal-oriented and retrospective habitual learning strategies. This arbitration is relevant dimensionally across psychi...
Gastrointestinal (GI) disorders are now widely recognized as a clinical symptom of autism spectrum disorder (ASD), and research into the microbiome-gut-brain axis is beginning to reveal the i...
DATE: January 19th, 2017TIME: 8:00AM PT, 11:00AM ETLiquid biopsies have the potential to be a less invasive method than traditional biopsies to detect advanced solid tumor mutational st...
DATE: November 9th, 2016
TIME: 9:00 AM PT, 12:00 PM ET
The screening and functional characterization of novel ligands for G-Protein Coupled Receptors (GPCR) remains a key focus in drug di...
DATE: October 19th, 2016
TIME: 8:00 AM PT, 11:00 AM ET
Comprehensive characterization of protein therapeutics through highly quantitative data is crucial in order to eliminate risk to pat...
DATE: October 11, 2016
TIME: 7:00am PT, 10:00am ET
Monoclonal antibodies (mAbs) have emerged as important therapeutics for the treatment of life-threatening diseases. The succ...
The ability to measure changes to DNA, RNA, and protein across cell types is crucial to understanding the immune response to the environment or therapeutic treatment. NanoString Technologies...
DATE: August 11, 2016
TIME: 11:00AM PST, 2:00PM ET, 7:00PM GMT
The central dogma that forms the backbone of molecular biology is that DNA codes for RNA (transcription) which then c...
Implementation of Capillary Electrophoresis (CE) technology in the biopharmaceutical industry is helping to characterize purity, heterogeneity, and identity of therapeutic...
The ExpiCHO transient expression system allows for the high titer production of a broad range of recombinant proteins. Due to the high titers observed for many proteins in the ExpiCHO system,...
9:00 AM PT, 11:00 AM CT, 12:00 PM ET
Epigenetics defines the set of distinct and heritable molecular mechanisms able to influence gene expression without altering the primary genetic seque...
DATE: April 4, 2016
TIME: 8:00am Pacific time, 11:00am Eastern time
The use of surface plasmon resonance to characterize protein:protein interactions is well established and has bee...
Given the challenges of replicating Parkinson’s disease in animal models, returning to models that are human-based and highly clinically characterized may provide the most successful pa...
Precision medicine requires understanding the mechanistic basis of complex disorders, and to precisely manipulate these mechanisms to better human health. This is partly enabled by the recent...
One of the primary goals of precision medicine is the aggregation and interpretation of deep, longitudinal patient-specific data in the context of the digital universe of information, using a...
DATE: February 2nd, 2016
TIME: 9am pacific time, 12pm eastern time
What is the most appropriate technology to empower your research?
Next generation sequencing (NGS) for RN...
Nanoparticle drug delivery systems (nanoDDS) are among the most promising avenues for effective treatment of many disorders, accomplished by the targeted release of chemotherapeutics, peptide...
DATE: November 4th, 2015
TIME: 11:00am Pacific time, 2:00pm Eastern time
AMPK, a highly conserved sensor of cellular energy status, is found in all eukaryotic cells and maintains met...
Biomarkers, with their associated “tsunami” of publications, represent what is arguably one of the largest areas of scientific inquiry in the history of biomedicine. Touted as the...
Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
Analytical ultracentrifugation (AUC) is a powerful technique for analyzing fundamental characteristics of macromolecules in solution, including size and shape, assembly state, and degree of p...
CALIXAR has developed an innovative detergent/surfactant based approach consisting on native isolation and stabilization of therapeutic membrane protein targets such as GPCRs, ion channels, t...
G protein coupled receptors (GPCRs) are the targets of 30-40% of all approved drugs. However many approaches successfully applied to drug discovery for soluble protein targets have made a lim...
Parkinson’s disease (PD) is characterized by the loss of dopamine and the disruption of brain circuits (basal ganglia and cortex) that are responsible for normal cognitive and motor per...
Our decisions are governed by a balance between prospective instrumental goal-oriented and retrospective habitual learning strategies. This arbitration is relevant dimensionally across psychi...
Gastrointestinal (GI) disorders are now widely recognized as a clinical symptom of autism spectrum disorder (ASD), and research into the microbiome-gut-brain axis is beginning to reveal the i...
DATE: January 19th, 2017TIME: 8:00AM PT, 11:00AM ETLiquid biopsies have the potential to be a less invasive method than traditional biopsies to detect advanced solid tumor mutational st...
DATE: November 9th, 2016
TIME: 9:00 AM PT, 12:00 PM ET
The screening and functional characterization of novel ligands for G-Protein Coupled Receptors (GPCR) remains a key focus in drug di...
DATE: October 19th, 2016
TIME: 8:00 AM PT, 11:00 AM ET
Comprehensive characterization of protein therapeutics through highly quantitative data is crucial in order to eliminate risk to pat...
DATE: October 11, 2016
TIME: 7:00am PT, 10:00am ET
Monoclonal antibodies (mAbs) have emerged as important therapeutics for the treatment of life-threatening diseases. The succ...
The ability to measure changes to DNA, RNA, and protein across cell types is crucial to understanding the immune response to the environment or therapeutic treatment. NanoString Technologies...
DATE: August 11, 2016
TIME: 11:00AM PST, 2:00PM ET, 7:00PM GMT
The central dogma that forms the backbone of molecular biology is that DNA codes for RNA (transcription) which then c...
Implementation of Capillary Electrophoresis (CE) technology in the biopharmaceutical industry is helping to characterize purity, heterogeneity, and identity of therapeutic...
The ExpiCHO transient expression system allows for the high titer production of a broad range of recombinant proteins. Due to the high titers observed for many proteins in the ExpiCHO system,...
9:00 AM PT, 11:00 AM CT, 12:00 PM ET
Epigenetics defines the set of distinct and heritable molecular mechanisms able to influence gene expression without altering the primary genetic seque...
DATE: April 4, 2016
TIME: 8:00am Pacific time, 11:00am Eastern time
The use of surface plasmon resonance to characterize protein:protein interactions is well established and has bee...
Given the challenges of replicating Parkinson’s disease in animal models, returning to models that are human-based and highly clinically characterized may provide the most successful pa...
Precision medicine requires understanding the mechanistic basis of complex disorders, and to precisely manipulate these mechanisms to better human health. This is partly enabled by the recent...
One of the primary goals of precision medicine is the aggregation and interpretation of deep, longitudinal patient-specific data in the context of the digital universe of information, using a...
DATE: February 2nd, 2016
TIME: 9am pacific time, 12pm eastern time
What is the most appropriate technology to empower your research?
Next generation sequencing (NGS) for RN...
Nanoparticle drug delivery systems (nanoDDS) are among the most promising avenues for effective treatment of many disorders, accomplished by the targeted release of chemotherapeutics, peptide...
DATE: November 4th, 2015
TIME: 11:00am Pacific time, 2:00pm Eastern time
AMPK, a highly conserved sensor of cellular energy status, is found in all eukaryotic cells and maintains met...
Biomarkers, with their associated “tsunami” of publications, represent what is arguably one of the largest areas of scientific inquiry in the history of biomedicine. Touted as the...
Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
Analytical ultracentrifugation (AUC) is a powerful technique for analyzing fundamental characteristics of macromolecules in solution, including size and shape, assembly state, and degree of p...
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