Deep Dive into Spatial Biology with MERFISH Technology and the MERSCOPE Ultra PlatformTM

In this presentation, Vizgen’s Instrument Product Manager will introduce you to their latest platform, the MERSCOPE® Ultra, for in situ spatial genomics powered by MERFISH technology. MERFISH (multiplexed error-robust fluorescence in situ hybridization) technology expands on the capabilities of single molecule FISH (smFISH) by using combinatorial labeling, sequential imaging, and error-robust barcoding to detect RNA with sub-micron accuracy. MERFISH has broad applications in both fundamental biology and medicine, ranging from basic science, to drug discovery, to clinical pathology. Given its ability to quantify RNAs across a wide range of abundances while preserving native context, MERFISH enables many applications of in situ transcriptomic analyses of individual cells in culture or complex tissues. 

 

Benefit from ultimate flexibility and efficiency without compromising MERFISH sensitivity as you dive deeper into the spatial organization of intact tissue. The MERSCOPE Ultra is a cutting-edge spatial biology platform that enables the mapping of transcripts across 3 cm2 of tissue on a single slide from a large variety of sample types including FFPE, fresh frozen, cultured cells and PFA fixed tissues.

 

During this webinar, Vizgen Director of Applications will also provide case study demonstrations of the performance of the MERSCOPE Ultra Platform.

 

Learning Objectives