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Next-generation transcriptome and miRNome sequencing are routinely performed on traditional cell or tissue samples, as well as more difficult samples such as FFPE samples and biofluids. Regar...
The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
One of the central tenants of biology is that our genetics—our genotype—influences the physical characteristics we manifest—our phenotype. But with more than 25,000 human ge...
CRISPR/Cas gene editing has become the gold standard for individual gene perturbations as well as high-throughput functional screenings, with a rapidly increasing demand for high-quality CRIS...
Arrayed gene knockout (KO) libraries represent a valuable resource for performing functional genomics screening. Current generation arrayed KO libraries for the whole human genome rely on eit...
To interpret genome sequence from telomere to telomere, it is helpful end-to-end haplotypes with single-molecule epigenetics overlays, via in situ omics at sub-cellular (20 nm) resolution an...
Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA. Although the critical role of DNA 5-methylcytosine (5mC) in the regulation of transcription is recognize...
In this webinar, we will discuss our most recent additions to our CRISPR protein portfolio, the GFP-SpCas9 and GFP-eCas9 fusion proteins. The two GFP-Cas9 fusion proteins offer great visualiz...
DATE: May 8, 2019TIME: 12:00am PDT In 2017 the first national cervical screening programs using human papillomavirus (HPV-based) primary screening were implemented. As these progr...
DATE: April 30, 2019TIME: 9:00am PDTAre you still handwashing all of your glassware? Are you considering buying an automated lab glassware washer? Does saving money get your attention...
DATE: April 30, 2019TIME: 8:00am PDTIumour-derived extracellular vesicles (EVs) are of increasing interest as a resource of diagnostic biomarkers. However, most EV assays require large...
D-dimer is used in the clinical evaluation of suspected venous thromboembolism (VTE). Newer measurement methods show high sensitivity for this test, and in combination with pretest probabilit...
Over the past 25 years many advances in techniques have been incorporated into infectious disease research. From genetically modified animals to advances in basic techniques that improve res...
Tuberculosis has killed more than one billion people in the last 200 years. It is the oldest and the deadliest human pathogen, recently surpassing HIV. Its adaptation to host and drug pressur...
Recent evidence indicates that the immunoglobulin (IG) gene loci reside within the most complex and variable regions of the human genome, characterized by elevated levels of single nucleotide...
Point-of-care testing (POCT) is diagnostic testing at the time and place of patient care in a physician’s office, an ambulance, a mobile clinic, at home or in hospital. Rapid POC testi...
“Emerging infections” are those that appear suddenly or are rapidly increasing in incidence or geographic range (e.g., HIV/AIDS, Ebola, SARS, Middle East Respiratory Syndrome [MER...
The Ebola virus disease outbreak in West Africa in 2014-2016 was the largest of its kind in history. This was the first outbreak that involved a randomized clinical trial for therapeutics, a...
To reduce the global burden diseases causes by infectious disease, including parasites and bacteria, scientists need better information about mechanisms of virulence, immune evasion, and drug...
Despite over 60+ years of research, the etiology of bacterial vaginosis (BV), the most common vaginal infection, remains controversial. Epidemiological data strongly suggest that BV is acquir...
DATE: April 24, 2019TIME: 9:30am PDTTicks are currently considered to be second only to mosquitoes as vectors of human infectious diseases in the world. Each tick species has preferred...
Learning objectives: Identify solutions in areas of coagulation that can be enhanced by implementing good laboratory practices and standard operating procedures Analyze re...
DATE: April 23, 2019TIME: 11:00am PDT, 2:00pm EDT Cataract, a clouding of the ocular lens, is the leading cause of blindness worldwide. Currently the only means of treatment i...
ABSTRACT Learning objectives: Highlight recent clinical trials describing use of DOACs Demonstrate if (ever) one needs to monitor DOACS Review best practice with respec...