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As obligate intracellular pathogens, viruses require host-derived nucleotides, amino acids, and lipids, among others, and the bioavailability of these metabolites can restrict or promote vir...
Since its discovery in late 2019 the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created a global pandemic of coronavirus disease 2019 (COVID-19). As of July of 2022, mo...
Recent outbreaks of Ebola virus (EBOV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have exposed our limited therapeutic options for such diseases and our poor understand...
The global effort to sequence millions of SARS-CoV-2 genomes has provided an unprecedented view of viral evolution. Characterizing how selection acts on SARS-CoV-2 is critical to developing...
Researchers are increasingly turning to RNA sequencing for gene expression analysis from challenging samples. These samples often include fine needle biopsies, micro-dissected tumors or high...
Pathogen detection and surveillance have become a high priority in both healthcare and environmental settings for the safety of patients and the general public. The COVID-19 pandemic highlig...
In the last decade or so, R&D into the human microbiome-based therapeutics and diagnostics has accelerated the widespread availability of next-generation DNA sequencing technologies that...
The lack of preparedness for detecting the highly infectious SARS-CoV-2 pathogen, the pathogen responsible for the COVID-19 disease, has caused enormous harm to public health and the economy...
Altered enteric microorganisms in concert with host genetics shape inflammatory bowel disease (IBD) phenotypes. However, insight is limited to bacteria and fungi. We found that eukaryotic vi...
Date: September 07, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Coronavirus disease 2019 (COVID-19) is especially severe in aged populations. Resolution of the COVID-19 pandemic ha...
Getting It Right: Preanalytical Impact on Coagulation Results Using a Case Study Approach According to published literature, up to 65% of errors occur in the preanalytical phase of laborator...
Antimicrobial resistance (AMR) detection and surveillance is a high priority in healthcare and environmental settings for the safety of both patients and the general public. However, working...
Critical in control of this pandemic is the ability to rapidly identify infectious individuals prior to their ability to infect others. With the introduction of better testing capacity and a...
This is a technical talk. Its objective is to provide details of virus sequencing, using SARS-CoV-2 as an example. Knowing the details, strengths, and limitations of virus sequencing will en...
Many clinically approved drugs that are prescribed to modulate human physiology are also potent antimicrobials at physiological concentrations. Recent systematic studies indicate that bacter...
Mammalian mucosal niches are colonized by a complex ecosystem of viruses, bacteria and fungi termed the microbiome. Unlike the gut microbiome, the vaginal microbiome is composed of small num...
Over 80% of opportunistic infections in humans are caused by microbial biofilms. Traditional methods of study for these infections have focused on single species yet there is a wealth of evi...
1. Identify the basic characteristics of the vaginal microbiota 2. Identify some ways in which the vaginal microbiota may protect against acquisition of sexually transmitted and urogenital i...
The vaginal microbiome is a critical component of female health. More than 30% of people with vaginas suffer from imbalances in the microbiome (e.g. bacterial vaginosis, yeast infections, an...
In all organisms, innate immune pathways sense infection and rapidly activate potent immune responses while maintaining a high degree of specificity to prevent inappropriate activation (auto...
Tuberculosis (TB), caused by the pathogen Mycobacterium tuberculosis (Mtb) remains one of the leading causes of morbidity and mortality worldwide. This presentation will summarise the epidem...
Human intestinal epithelial cells (hIECs) are arranged as a monolayer of cells and provide the first line of defense against invading pathogens. Upon viral infection hIECs upregulate type I...
Given its ability to isolate pathogens, nuclei, and immune cells for downstream applications, cell sorting is an essential tool for immunological studies. Yet, the potential for aerosol form...
Date: September 06, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Next Generation Sequencing (NGS) provides comprehensive genomic information about disease, development, and other bi...
NGS library preparation can be a long, multi-step process, but it is essential for proper sample management and reproducible results. Automating this process reduces costs, frees up research...
We live in a revolutionary era during which technology is leading to amazing advances in medicine. Parallel and aided by the development of artificial intelligence (AI) are the emergence of...
Human respiratory syncytial virus (hRSV) is a significant cause of lower respiratory tract infections in children under the age of 5, the elderly, and immunocompromised individuals, leading...
As obligate intracellular pathogens, viruses require host-derived nucleotides, amino acids, and lipids, among others, and the bioavailability of these metabolites can restrict or promote vir...
