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One of the central tenants of biology is that our genetics—our genotype—influences the physical characteristics we manifest—our phenotype. But with more than 25,000 human g...
In this webinar, we present a case study on Lynch syndrome (LS), a hereditary condition characterized by a high risk of colorectal cancer, endometrial cancer, and other neoplasia that typica...
Advancements in immuno-oncology have been moving at an ever-quickening pace. From the development of new CAR-T therapies to a better understanding of the mechanism of action of monoclonal an...
Effective immunotherapy of pancreatic ductal adenocarcinoma (PDAC) is hampered by the lack of suitable tumor-specific antigens. To address this challenge, we have combined high-throughput fl...
Background: Localized prostate cancer is notable for tumor heterogeneity, and immune heterogeneity within tumor versus benign areas. B7-H3, a member of the B7 superfamily, is highly expresse...
Date: October 6, 2021 Time: 9:00am (PDT), 12:00pm (EDT) ANTIBODY TITRATION is critical to the success of any flow cytometry experiment. This is even more so in microflow cytometric analysis...
There is considerable research being conducting on the topic of health disparities. It is important to understand why these health disparities exist as well as what is contributing to so man...
COSMIC is the world’s largest and most comprehensive somatic mutations resource. COSMIC’s contents are manually curated by PhD-level experts from high-quality scientific literatu...
African American women face a lower risk of being diagnosed with breast cancer as compared to Caucasian-American women, yet they paradoxically face an increased breast cancer mortality hazar...
Date: October 05, 2021 Time: 7:00am (PDT), 10:00am (EDT) After new users become familiar with flow cytometry instrumentation and learn how to set up the instrument and acquire data, the next...
Date: October 5, 2021 Time: 6:00am (PDT), 9:00am (EDT), 3:00pm (CEST) Dr. Markus Kostrzewa shall elaborate the progress that has been made in the Research & Development department of Bru...
Date: September 30, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Centrifugation is an indispensable laboratory application for separating and purifying a range of biological materials. Although a...
Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
The recent outbreak of the Coronavirus Disease 2019 (COVID-19) has spread all over the world and raised global concerns. Rapid and early detection of the novel coronavirus SARS-CoV-2, the ca...
The COVID-19 pandemic demonstrated the need for rapid, accurate diagnostic tests that could be developed and deployed quickly. Since the company’s founding in 2018, Mammoth has been ad...
Rapid, accurate, and wide-spread COVID-19 testing is essential for contact tracing, timely triaging of patients, and viral monitoring. The current gold standard for COVID-19 testing is RT-PC...
The advent of CRISPR-Cas (Clustered regularly interspaced short palindromic repeats-CRISPR associated) makes it feasible to target/edit the genome with precision. Most of the CRSIPR-Cas syst...
Over the past ten years, CRISPR technology has revolutionized genome engineering, as reflected by the recently awarded Nobel Prize. Nevertheless, the process of performing and characterizing...
Performance. Automation. Convenience. Versatility. Those three elements exemplify the Miltenyi Biotec family of flow cytometers. Designed to support the field of flow cytometry, the MACSQuan...
Multi-target screening can offer great insight into the genetic pathways in drug resistance and disease. RNAi and the fast pace of CRISPR technology development has brought sophisticated opt...
Date: September 29, 2021 Time: 10:00am (PDT), 1:00pm (EDT) Multiplexed tissue analysis is a powerful technique that allows comparisons of cell-type locations and cell-type interactions withi...
RNA plays important and diverse roles in biology, but molecular tools to manipulate and measure RNA are limited. We demonstrate that RNA-targeting CRISPR effector Cas13 and novel RNA targeti...
Nucleic acid testing is crucial for the prevention, diagnosis and treatment monitoring of many diseases in medicine. Over the last years, microRNAs (miRNAs), short non-coding RNAs, as biomar...
Date: September 28, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Standardization and reproducibility are prerequisites for peripheral blood mononuclear cell (PBMC) generation from donor or patient...
Date: September 28, 2021 Time: 8:00am (PDT), 11:00am (EDT) Flow cytometry provides many advantages including single-cell quantitative analysis, high sample throughput, and multiplex cell cha...