Follow a curation of discoveries and updates in immunology focusing on immune responses to infectious disease, structure and function, and developments in the defense against infection by watching and engaging in these webinars.
In this session we will use a set of reads enriched for viral sequences and sequences from wastewater treatment plants. Specifically the aim is to assemble whole SARS-CoV-2 genomes from such...
Despite the immense promise of cancer immunotherapies, significant challenges have been mounting to overcome treatment resistance and to improve efficacy. Strategies such as the combination...
The immune system evolved to protect us against pathogen invasion and to maintain tissue homeostasis. Fundamental for these functions are the interferons (IFNs), a group of cytokines that be...
Molecular diagnostic tests are currently used for infectious disease testing due to the superior sensitivity and specificity that can be obtained. Due to the success that has been obtained w...
Prostate cancers are considered immunologically ‘cold’ tumors given the very few patients who respond to checkpoint inhibitor therapy (CPI). Recently, enrichment of interferon st...
Advancements in immuno-oncology have been moving at an ever-quickening pace. From the development of new CAR-T therapies to a better understanding of the mechanism of action of monoclonal an...
This webinar will highlight the research solutions that Miltenyi Biotec has to offer for those investigating the roles of Tregs, NK cells, and Macrophages in the context of the tumor microen...
Learning Objectives: 1. Define applications of approved and experimental (multiplexing IF) biomarker assessment in Immuno-Oncology 2. Define bottlenecks and areas of improvement to current t...
Primary resistance to CD19-directed chimeric antigen receptor T-cell therapy (CART19) occurs in 10% to 20% of patients with acute lymphoblastic leukemia (ALL); however, the mechanisms of thi...
Plant-infecting viruses cause significant losses to agriculture, including to staple crops such as wheat, maize, and rice. Preventing and managing endemic and emerging plant diseases is an o...
Over years, HMGB1 has increasingly attracted the attention of all kinds of researchers. It is one of the most intriguing molecules within the complete arsenal of proteins of the innate immun...
Immune checkpoint blockade has revolutionized the treatment for patients with cancer. Great efforts remain to better understand resistant mechanisms to treatment as well as means to improve...
Cells in their natural environment are surrounded by a complex extracellular matrix that provides structure and functional cues to the surrounding cells. Hydrogels can be used to approximate...
The Coronavirus disease 2019 (COVID-19) pandemic poses an unprecedented challenge for public health, which is caused by infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV...
Discover how experience in utilizing a digital lab platform can elevate research workflows. Margriet will share insights, practical strategies, and success stories that demonstrate the benef...
The future of cancer care is contingent on better understanding of molecular, clinical, and outcome data. This can be achieved by leveraging collaborative affiliations and networks locally a...
Severe acute respiratory syndrome coronavirus (SARS-CoV-2) is a novel virus that causes COVID-19 and has considerable variability in clinical outcomes among infected patients. The GENCOV stu...
SARS-CoV-2 testing is now facing increasing challenges in the face of an ongoing pandemic with the emergence of new variants and waning vaccine immunity. Increasing evidence supports the cor...
Over the past 10 years, we have come to a greater understanding of the pathogenesis of men who succumb to prostate cancer. One critical aspect is the role of molecular drivers in patients wi...
We recently determined that concurrent inhibition of autophagy, using the lysosomal inhibitor chloroquine (CQ), and of ERK, using a small molecule ERK inhibitor (ERKi), synergistically suppr...
Individuals with Lynch syndrome (LS) are prone to develop early-onset mismatch repair deficient (dMMR) colorectal- and endometrial cancers due to germline pathogenic variants (PVs) in one of...
The microenvironment of many solid tumors impedes many immunotherapeutic treatments by inhibiting the effector functions of many classes of anti-tumor immune cells, including effector T cell...
Technological advances in Artificial Intelligence (AI), particularly deep learning, have demonstrated remarkable progress in image-recognition tasks. Methods ranging from convolutional neura...
Summary: Cancer neoantigens are highly specific to the tumor, potently immunogenic and can be targeted by both vaccines and engineered cellular therapies. This talk will introduce the defini...
The ultimate promise of tumor immunotherapy is dependent on the generation of effective immunity against cancer, including CD4 and CD8 T cell responses. However, activating T cells in cancer...
There are currently several different FDA approved radiopharmaceuticals being used in both large academic and small practice settings to accurately stage and identify local and metastatic pr...
Chimeric antigen receptor (CAR) T cells have demonstrated significant success in treating relapsed or treatment-refractory hematologic malignancies in the clinic, inducing remissions in 70-9...
In this session we will use a set of reads enriched for viral sequences and sequences from wastewater treatment plants. Specifically the aim is to assemble whole SARS-CoV-2 genomes from such...
