Learn from the latest webinars about newly released neuroscience research and advances in experimental techniques. Topics include research news in neuroscience, neurology, psychology, brain science and cognitive sciences.
Localizing and identifying neuronal patterns that generate pathological brain signals may assist with tissue resection and intervention strategies in patients with neurological and psychiatri...
Speech neuroprostheses have the potential to restore communication to people living with paralysis, but naturalistic speed and expressivity are elusive. Here we use high-density surface reco...
Developing new diagnostic and therapeutic tools for brain disorders is an ethical imperative and conducting human research with neural devices is a key step towards achieving that goal. Condu...
Learning is often an emotional process. Emotional stimuli with different valences, such as threat and reward, can transform an otherwise neutral sensory input into one that can trigger disti...
Systems neuroscience offers new and powerful conceptual frameworks for testing the fundamental brain mechanisms that support behavior. More recently, modern neurotechnologies with translation...
Humans have a remarkable ability to flexibly interact with the environment. A compelling demonstration of this cognitive flexibility is our ability to perform complex, yet previously un-pract...
How does a low-level sensory representation rise into conscious awareness? What determines whether higher-order cortical areas have access to the representational content in sensory regions?...
Clathrin mediated endocytosis (CME) at pre-synaptic terminals is functionally coupled to neuro-transmitter release. Like other cytosolic proteins, clathrin is synthesized in cell-bodies and c...
Determining the copy number of SMN1 and SMN2 genes is notoriously difficult due to the high level of homology between the two genes. These genes, that are associated with spinal muscular atro...
The rapid formation of new memories and the recall of old memories to inform decisions is essential for human cognition, but the underlying neural mechanisms remain poorly understood. We util...
Neuroscience is experiencing an exciting era of integrating novel materials and tools to record neural activity made possible through significant advances in materials science, electrical en...
Complex behaviors are often driven by an internal model, which integrates sensory information over time and facilitates long-term planning to reach subjective goals. {\color{rev}A fundamenta...
Threshold-linear networks (TLNs) display a wide variety of nonlinear dynamics including multistability, limit cycles, quasiperiodic attractors, and chaos. Over the past few years, we have de...
Targeted stimulation of the brain has the potential to treat mental illnesses but designing an appropriate protocol requires a multitude of choices. I will describe an approach to help desig...
The dopamine D4 receptor (D4R) is enriched in the prefrontal cortex where it plays important roles in cognition, attention, decision making and executive function. Novel D4R-selective ligand...
Treatment-resistant depression is an immense source of disability and suffering, and represents a major unmet clinical need for innovative and effective therapies. Deep brain stimulation tri...
The NIH BRAIN Initiative aims to develop new tools and neurotechnologies to transform our understanding of brain function in health and disease. That knowledge is critical to enable novel the...
Recent advances in machine learning have shown that deep neural networks (DNNs) can provide powerful and flexible models of neural sensory processing. In the auditory system, standard linear...
Cortical circuits often receive multiple inputs from upstream populations with non-overlapping stimulus tuning. Both the feedforward and recurrent architectures of the receiving cortical lay...
One role of theory is in guiding future experiments: What should we aim to measure? Which experimental results should we be surprised about? I will argue here that simple random networks mod...
The intrinsic activity of the brain is organized into networks and motifs that vary over time. To understand how coordinated macroscale patterns of intrinsic activity flow across the brain&r...
Learning Objectives: 1. Delineate the goals of studies of brain, computation and behavior and how they can be integrated. 2. Describe how neuromodulators such as oxytocin transform circuits...
Animal models present a unique opportunity to understand molecular mechanisms of pathological changes involved in cognitive dysfunction in neurological disorders. However, most of the work f...