mouse monoclonal IgG1; DDX38 Antibody (A-8) is an IgG1 κ mouse monoclonal DDX38 antibody (also designated DHX38 antibody or PRP16 antibody) that detects the DDX38 protein of mouse, rat and human origin by WB, IP, IF and ELISA. DDX38 Antibody (A-8) is available as both the non-conjugated anti-DDX38 antibody form, as well as multiple conjugated forms of anti-DDX38 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. DDX38 (Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16) is a 1,227 amino acid protein encoded by the human gene DDX38. DDX38 belongs to the DEAD-box helicase family (DEAH subfamily, PRP16 sub-subfamily) and contains one helicase ATP-binding domain and one helicase C-terminal domain. DDX38 is believed to be a probable ATP-dependent RNA helicase. RNA helicases are highly conserved enzymes that utilize the energy derived from NTP hydrolysis to modulate the structure of RNA. RNA helicases participate in all biological processes that involve RNA, including transcription, splicing and translation.