mouse monoclonal IgG1; EF-2 Antibody (C-9) is an IgG1 κ mouse monoclonal EF-2 antibody (also designated EEF2 antibody, EF2 antibody, Eukaryotic Translation Elongation Factor 2 antibody, Polypeptidyl-TRNA Translocase antibody, Elongation Factor 2 antibody, EEF-2 antibody, or SCA26 antibody) that detects the EF-2 protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. EF-2 Antibody (C-9) is available as both the non-conjugated anti-EF-2 antibody form, as well as multiple conjugated forms of anti-EF-2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Two elongation factors (EF) EF-Tu and EF-2 participate in the elongation phase during protein biosynthesis on the ribosome and their functional cycles depend on GTP binding and its hydrolysis. EF-Tu (also designated mitochondrial precursor p43) and EF-2 are multidomain GTPases with essential functions in translation, and they both bind to the same site on the ribosome where their low intrinsic GTPase activities are strongly stimulated. EF-Tu plays a central role in the fast and accurate delivery of aminoacyl-tRNAs to the translating ribosome. In addition, EF-Tu protects the aminoester bond against hydrolysis until a correct match between the codon on mRNA and the anticodon on tRNA can be achieved. EF-2 supports the translocation of tRNAs and of mRNAs on the ribosome so that a new codon can be exposed for decoding.