Companies / Santa Cruz Biotechnology / PSR (H-7) Alexa Fluor® 680
Santa Cruz Biotechnology

PSR (H-7) Alexa Fluor® 680 | Santa Cruz Biotechnology

mouse monoclonal IgG1; PSR Antibody (H-7) is an IgG1 κ mouse monoclonal PSR antibody (also designated Jumonji Domain Containing 6 antibody, Arginine Demethylase And Lysine Hydroxylase antibody, Phosphatidylserine Receptor antibody, Jumonji Domain-Containing Protein 6 antibody, Histone Arginine Demethylase JMJD6 antibody, Peptide-Lysine 5-Dioxygenase JMJD6 antibody, Jumonji Domain Containing 6 antibody, Lysyl-Hydroxylase JMJD6 antibody, PTDSR1 antibody, or PTDSR antibody) that detects the PSR protein of human origin by WB, IP, IF, IHC(P) and ELISA. PSR Antibody (H-7) is available as both the non-conjugated anti-PSR antibody form, as well as multiple conjugated forms of anti-PSR antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Cells undergoing apoptosis lose the asymmetry of plasma membrane phospholipids, and phosphatidylserine is exposed on the outer surface of the membrane. The phosphatidylserine receptor (PSR) specifically recognizes phosphatidylserine and this binding triggers the phagocytosis of apoptotic cells by either macrophages or dendritic cells. PSR is expressed on the surface of macrophages, fibroblasts, and epithelial cells, and it has been detected in high levels in heart, skeletal muscle, and kidney tissues and is extensively glycosylated. The mammalian phosphatidylserine receptor displays significant homology to Caenorhabditis elegans and Drosophila melanogaster proteins, which suggests that PSR has been conserved throughout phylogeny.

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ABOUT THE COMPANY

Santa Cruz Biotechnology is a world leader in the development of products for the biomedical research market. Over the past 30+ years, the Company has focused on the ongoing development of research antibodies, siRNA and CRISPR Gene editing tools, biochemicals, labware and more recently has expanded into animal health care products. Santa Cruz Biotechnology has the highest commitment to quality and customer service.