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Santa Cruz Biotechnology

TAF I p110 (C-10) Alexa Fluor® 680 | Santa Cruz Biotechnology

mouse monoclonal IgG1; TAF I p110 Antibody (C-10) is an IgG1 κ mouse monoclonal TAF I p110 antibody (also designated TAF I p110 antibody) that detects the TAF I p110 protein of human origin by WB, IP, IF and ELISA. TAF I p110 Antibody (C-10) is available as both the non-conjugated anti-TAF I p110 antibody form, as well as multiple conjugated forms of anti-TAF I p110 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. For gene transcription governed by RNA polymerase I, the human transcription factor SL1 (mouse TIF-IB) directs the assembly of initiation complexes at the prompter. Like TFIID, which directs transcription by RNA polymerase II, SL1/TIF-IB contains the TATA-binding protein (TBP) and a set of TBP-associated factors (TAFs). The three TAF I subunits, hTAF I p110, hTAF I p63 and hTAF p48 (or mouse TAF I p95, TAF I p68 and TAF I p48) are all integral components of SL1/TIF-IB. The mutually exclusive binding of either TAF I or TAF II subunits to TBP is believed to direct the formation of promoter- and RNA polymerase-specific complexes.

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ABOUT THE COMPANY

Santa Cruz Biotechnology is a world leader in the development of products for the biomedical research market. Over the past 30+ years, the Company has focused on the ongoing development of research antibodies, siRNA and CRISPR Gene editing tools, biochemicals, labware and more recently has expanded into animal health care products. Santa Cruz Biotechnology has the highest commitment to quality and customer service.