mouse monoclonal IgG2a; DDX36 Antibody (B-6) is an IgG2a κ mouse monoclonal DDX36 antibody (also designated DHX36 antibody) that detects the DDX36 protein of mouse, rat and human origin by WB, IP, IF and ELISA. DDX36 Antibody (B-6) is available as both the non-conjugated anti-DDX36 antibody form, as well as multiple conjugated forms of anti-DDX36 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure. Specifically, DEAD box proteins are involved in translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, members of this family may be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX30, DDX35 and DDX36 each contain 1 helicase ATP-binding domain and 1 helicase C-terminal domain. DDX36 (DEAH box protein 36), also known as MLE-like protein 1 and RNA helicase associated with AU-rich element ARE, is a 1,008 amino acid protein that is expressed in testis and may function in sex development and spermatogenesis.DDX36 plays a role in degradation and deadenylation of mRNAs that contain the consensus ARE sequence element in their 3'-UTR. There are three isoforms of DDX36 that exist as a result of alternative splicing events.