mouse monoclonal IgG2a; Adipsin Antibody (D10/4) is an IgG2a κ mouse monoclonal Adipsin antibody (also designated CFAD antibody, Complement Factor D antibody, Properdin Factor D antibody, D Component Of Complement (Adipsin) antibody, C3 Convertase Activator antibody, Adipsin antibody, or ADN antibody) that detects the Adipsin protein of human origin by WB, IP, IF and IHC(P). Adipsin Antibody (D10/4) is available as both the non-conjugated anti-Adipsin antibody form, as well as multiple conjugated forms of anti-Adipsin antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Adipsin is the mouse homolog of the previously described human complement Factor D, a serine protease, which is now designated human Adipsin. Human Adipsin is highly expressed in and secreted by adipose tissue, and it has also been found in monocytes and macrophages. Rodent Adipsin has only been detected in high levels in adipose tissue. It has been shown that complement factor B, when complexed with activated complement component C3, is cleaved by Adipsin. While low expression of Adipsin has been confirmed in obese mice with hypothalamic defects, this inverse correlation between Adipsin expression and obesity has not been demonstrated in humans.