mouse monoclonal IgG1; golgin 45 Antibody (E-3) is an IgG1 κ mouse monoclonal golgin 45 antibody (also designated golgin 45 antibody) that detects the golgin 45 protein of human origin by WB, IP, IF and ELISA. golgin 45 Antibody (E-3) is available as both the non-conjugated anti-golgin 45 antibody form, as well as multiple conjugated forms of anti-golgin 45 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Golgin 45, also known as JEM-1 or Basic Leucine Zipper Nuclear Factor 1, is a 400 amino acid protein that localizes to the lumen of the golgi apparatus. The primary function of golgin 45 is to maintain normal golgi structure and to facilitate protein transport from the endoplasmic reticulum to the cell surface. The latter process is regulated primarily through the interaction of golgin 45 and GRASP55, which, together, form a Rab 2 effector complex.Excluding formation of a Rab 2 complex, golgin 45 does not interact with any other golgi Rab proteins. Golgin 45 is expressed as two isoforms, one of which localizes to the nucleus and is thought to function as a transcription factor.